[Severe decompensation of hepatitis e in a patient with autoimmune hepatitis: a case report].

V. Valenzuela, J. Pinto, M. Padilla, A. Piscoya, R. De Los Rios, Y. Surco, E. Bravo, J. Huerta-Mercado

Resultado de la investigación: Contribución a una revistaReseña científicaInvestigaciónrevisión exhaustiva

2 Citas (Scopus)

Resumen

We report the case of a patient who initially made the diagnosis of acute hepatitis E virus with a clinical picture of jaundice with elevated liver enzymes and HEV IgM (+), but chronic evolution (More than 6 months) without being an immunosuppressed patient, forced us to exclude different causes that may produce chronic liver disease. And hypergammaglobulinemia was detected in liver biopsy: interface hepatitis, mixed inflammatory infiltrate with predominance of lymphocytes, and presence of portal-portal fibrous tracts, suggestive of severe active chronic hepatitis may be secondary to autoimmune hepatitis associated with hepatitis virus infection E. With these findings, we decided to start treatment for autoimmune hepatitis with prednisone and azathioprine, leading to a decrease in transaminases and coagulation profile to normal, which helped confirm the diagnosis of autoimmune hepatitis and decompensated manifested by acute virus infection of hepatitis E. Full report the case and a review of the literature.
Idioma originalInglés estadounidense
Páginas (desde-hasta)187-191
Número de páginas5
PublicaciónRevista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú
EstadoPublicada - 1 ene 2012

Huella dactilar

Autoimmune Hepatitis
Viruses
Liver
Hepatitis
Virus Diseases
Hepatitis E
Hepatitis E virus
Hypergammaglobulinemia
Hepatitis Viruses
Lymphocytes
Biopsy
Azathioprine
Chronic Hepatitis
Prednisone
Transaminases
Jaundice
Coagulation
Immunoglobulin M
Liver Diseases
Chronic Disease

Citar esto

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title = "[Severe decompensation of hepatitis e in a patient with autoimmune hepatitis: a case report].",
abstract = "We report the case of a patient who initially made the diagnosis of acute hepatitis E virus with a clinical picture of jaundice with elevated liver enzymes and HEV IgM (+), but chronic evolution (More than 6 months) without being an immunosuppressed patient, forced us to exclude different causes that may produce chronic liver disease. And hypergammaglobulinemia was detected in liver biopsy: interface hepatitis, mixed inflammatory infiltrate with predominance of lymphocytes, and presence of portal-portal fibrous tracts, suggestive of severe active chronic hepatitis may be secondary to autoimmune hepatitis associated with hepatitis virus infection E. With these findings, we decided to start treatment for autoimmune hepatitis with prednisone and azathioprine, leading to a decrease in transaminases and coagulation profile to normal, which helped confirm the diagnosis of autoimmune hepatitis and decompensated manifested by acute virus infection of hepatitis E. Full report the case and a review of the literature.",
author = "V. Valenzuela and J. Pinto and M. Padilla and A. Piscoya and {De Los Rios}, R. and Y. Surco and E. Bravo and J. Huerta-Mercado",
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[Severe decompensation of hepatitis e in a patient with autoimmune hepatitis: a case report]. / Valenzuela, V.; Pinto, J.; Padilla, M.; Piscoya, A.; De Los Rios, R.; Surco, Y.; Bravo, E.; Huerta-Mercado, J.

En: Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú, 01.01.2012, p. 187-191.

Resultado de la investigación: Contribución a una revistaReseña científicaInvestigaciónrevisión exhaustiva

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AU - Padilla, M.

AU - Piscoya, A.

AU - De Los Rios, R.

AU - Surco, Y.

AU - Bravo, E.

AU - Huerta-Mercado, J.

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N2 - We report the case of a patient who initially made the diagnosis of acute hepatitis E virus with a clinical picture of jaundice with elevated liver enzymes and HEV IgM (+), but chronic evolution (More than 6 months) without being an immunosuppressed patient, forced us to exclude different causes that may produce chronic liver disease. And hypergammaglobulinemia was detected in liver biopsy: interface hepatitis, mixed inflammatory infiltrate with predominance of lymphocytes, and presence of portal-portal fibrous tracts, suggestive of severe active chronic hepatitis may be secondary to autoimmune hepatitis associated with hepatitis virus infection E. With these findings, we decided to start treatment for autoimmune hepatitis with prednisone and azathioprine, leading to a decrease in transaminases and coagulation profile to normal, which helped confirm the diagnosis of autoimmune hepatitis and decompensated manifested by acute virus infection of hepatitis E. Full report the case and a review of the literature.

AB - We report the case of a patient who initially made the diagnosis of acute hepatitis E virus with a clinical picture of jaundice with elevated liver enzymes and HEV IgM (+), but chronic evolution (More than 6 months) without being an immunosuppressed patient, forced us to exclude different causes that may produce chronic liver disease. And hypergammaglobulinemia was detected in liver biopsy: interface hepatitis, mixed inflammatory infiltrate with predominance of lymphocytes, and presence of portal-portal fibrous tracts, suggestive of severe active chronic hepatitis may be secondary to autoimmune hepatitis associated with hepatitis virus infection E. With these findings, we decided to start treatment for autoimmune hepatitis with prednisone and azathioprine, leading to a decrease in transaminases and coagulation profile to normal, which helped confirm the diagnosis of autoimmune hepatitis and decompensated manifested by acute virus infection of hepatitis E. Full report the case and a review of the literature.

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