Serological and molecular detection of dengue virus in animals: A systematic review and meta-analysis

D. Katterine Bonilla-Aldana*, Marcela María Rodas-Fuenmayor, Luisa María Ruiz-Aristizabal, Juan R. Ulloque-Badaracco, Esteban A. Alarcón-Braga, Enrique A. Hernandez-Bustamante, Juan C. Cabrera-Guzman, Ricardo R. Ulloque-Badaracco, Vicente A. Benites-Zapata, Alfonso J. Rodriguez-Morales

*Autor correspondiente de este trabajo

Producción científica: Contribución a una revistaArtículo de revisiónrevisión exhaustiva

Resumen

Introduction: Dengue is a vector-borne disease, especially important in tropical and subtropical areas. The first presentation of many arboviral diseases occurred mainly in animals, including multiple Alphaviruses and Flaviviruses, such as dengue. Objective: To determine the serological and molecular frequency of the dengue virus in animals. Methods: A systematic literature review was carried out in five databases for the proportion of animals infected with dengue, defined by molecular and serological tests. A meta-analysis was performed using a randomeffects model to calculate the pooled prevalence and 95% confidence intervals (CI). Cochran?s Q test and the I2 statistic were used to assess the heterogeneity between the two studies. Results: The presence of dengue in bats, primates, birds, sheep, horses, cattle, pigs, rodents and buffaloes, according to serological methods, had a prevalence of 10%, 29%, 8%, 1%, 11%, 0%, 49%, 2%, 7%, respectively. According to molecular methods, the presence of dengue in bats had a seroprevalence of 6.0%. Conclusion: The present study confirms the presence of the Dengue virus in a large group of animal species, with potential implications as possible reservoirs of this virus, raising the possibility of zoonotic transmission.

Idioma originalInglés
Páginas (desde-hasta)183-201
Número de páginas19
PublicaciónInfezioni in Medicina
Volumen32
N.º2
DOI
EstadoPublicada - 2024

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