SAT0581 Poor health-related quality of life (hrqol) and fatigue are associated with a higher work productivity impairment in systemic lupus erythematosus (sle) patients

Cristina Reategui Sokolova, Rocío Violeta Gamboa Cárdenas, Mariela Medina, Francisco Zevallos Miranda, Paola Alejandra Zeña Huancas, Claudia Elera-Fitzcarrald, Victor Pimentel Quiroz, Jose Alfaro Lozano, Cesar Pastor Asurza, Risto Perich Campos, Zoila Rodriguez Bellido, Graciela S. Alarcon, Manuel F. Ugarte-Gil

Resultado de la investigación: Contribución a una revistaResumen de conferenciaInvestigaciónrevisión exhaustiva

Resumen

Background: Because most patients with SLE are in their productive-age years, the ability to maintain a gainful employment is fundamental for both, the patient and society at large. It is thus quite important to determine the work and non-work factors that are associated with work productivity impairment in these patients.Objectives: To determine the factors associated with absenteeism (percentage of the time missed from scheduled work-time over the preceding 7 days, due to SLE), presenteeism (percentage of time from scheduled work-time where productivity was impaired while patient was at work, over the preceding 7 days, due to SLE) and overall work impairment (combination of absenteeism and presenteeism) in patients with SLE.Methods: A total of 133 consecutive (1997 American College of Rheumatology (ACR) criteria) working patients with SLE were assessed between October 2017 and December 2018, using a standardized data collection form. Sociodemographic, disease and work-related variables were collected. Disease activity was ascertained with the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI); disease damage with the Systemic Lupus International Collaborating Clinics/ACR Damage Index (SDI); health-related quality of life was assessed with the LupusQoL and fatigue with the FACIT-Fatigue (Functional Assessment of Chronic Illness Therapy-Fatigue). Work Productivity and Activity Impairment (WPAI) was assessed with the respective questionnaire; absenteeism and presenteeism due to overall health and symptoms during the past 7 days were scored. Linear regression models were performed to determine the factors associated with absenteeism, presenteeism and overall work impairment. Potential factors included were age at diagnosis, gender, socioeconomic status, educational level, SLEDAI, SDI, FACIT- Fatigue and the components of the LupusQoL.Results: The mean age at diagnosis was 32.2 years (11.8); 121 (91.7%) were female. Nearly all patients were Mestizo. Mean years of education was 14.1 (2.6). The mean disease duration was 11.9 (7.5) years. Mean SLEDAI was 2.9 (4.0), and mean SDI was 1 (1.4). The mean percent of time for absenteeism was 5.0 (12.9), it was 28.5 (26.4) for presenteeism, and it was 31.3 (27.2) for overall work impairment. In the multiple regression analysis, factors associated with absenteeism were disease duration (B=-0.34; SE=0.12; p=0.007); pain (B=-0.14; SE=0.06; p=0.046); intimate relationship (B=-0.07; SE=0.03; p=0.046) and emotional health (B=0.16; SE=0.06; p=0.006), with presenteeism were physical health (B=-0.43; SE=0.14; p=0.002) and FACIT (B=-0.87; SE=0.30; p=0.005) and with overall work impairment were pain (B=-0.40; SE=0.11; p=0.001) and FACIT-Fatigue (B=-0.74; SE=0.28; p=0.010).Conclusion: A poor HRQoL and higher levels of fatigue were associated with a higher percentage of absenteeism, presenteeism and overall work impairment in SLE patients. Addressing the factors related to HRQoL and Fatigue may have significant impact on work performance among SLE patients.Disclosure of Interests: None declared
Idioma originalEspañol (Perú)
PublicaciónAnnals of the Rheumatic Diseases
DOI
EstadoPublicada - 1 jun 2019

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Sokolova, Cristina Reategui ; Gamboa Cárdenas, Rocío Violeta ; Medina, Mariela ; Miranda, Francisco Zevallos ; Zeña Huancas, Paola Alejandra ; Elera-Fitzcarrald, Claudia ; Quiroz, Victor Pimentel ; Lozano, Jose Alfaro ; Asurza, Cesar Pastor ; Campos, Risto Perich ; Bellido, Zoila Rodriguez ; Alarcon, Graciela S. ; Ugarte-Gil, Manuel F. / SAT0581 Poor health-related quality of life (hrqol) and fatigue are associated with a higher work productivity impairment in systemic lupus erythematosus (sle) patients. En: Annals of the Rheumatic Diseases. 2019.
@article{8e168895f94a4d2d9f9c7afaf8af9304,
title = "SAT0581 Poor health-related quality of life (hrqol) and fatigue are associated with a higher work productivity impairment in systemic lupus erythematosus (sle) patients",
abstract = "Background: Because most patients with SLE are in their productive-age years, the ability to maintain a gainful employment is fundamental for both, the patient and society at large. It is thus quite important to determine the work and non-work factors that are associated with work productivity impairment in these patients.Objectives: To determine the factors associated with absenteeism (percentage of the time missed from scheduled work-time over the preceding 7 days, due to SLE), presenteeism (percentage of time from scheduled work-time where productivity was impaired while patient was at work, over the preceding 7 days, due to SLE) and overall work impairment (combination of absenteeism and presenteeism) in patients with SLE.Methods: A total of 133 consecutive (1997 American College of Rheumatology (ACR) criteria) working patients with SLE were assessed between October 2017 and December 2018, using a standardized data collection form. Sociodemographic, disease and work-related variables were collected. Disease activity was ascertained with the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI); disease damage with the Systemic Lupus International Collaborating Clinics/ACR Damage Index (SDI); health-related quality of life was assessed with the LupusQoL and fatigue with the FACIT-Fatigue (Functional Assessment of Chronic Illness Therapy-Fatigue). Work Productivity and Activity Impairment (WPAI) was assessed with the respective questionnaire; absenteeism and presenteeism due to overall health and symptoms during the past 7 days were scored. Linear regression models were performed to determine the factors associated with absenteeism, presenteeism and overall work impairment. Potential factors included were age at diagnosis, gender, socioeconomic status, educational level, SLEDAI, SDI, FACIT- Fatigue and the components of the LupusQoL.Results: The mean age at diagnosis was 32.2 years (11.8); 121 (91.7{\%}) were female. Nearly all patients were Mestizo. Mean years of education was 14.1 (2.6). The mean disease duration was 11.9 (7.5) years. Mean SLEDAI was 2.9 (4.0), and mean SDI was 1 (1.4). The mean percent of time for absenteeism was 5.0 (12.9), it was 28.5 (26.4) for presenteeism, and it was 31.3 (27.2) for overall work impairment. In the multiple regression analysis, factors associated with absenteeism were disease duration (B=-0.34; SE=0.12; p=0.007); pain (B=-0.14; SE=0.06; p=0.046); intimate relationship (B=-0.07; SE=0.03; p=0.046) and emotional health (B=0.16; SE=0.06; p=0.006), with presenteeism were physical health (B=-0.43; SE=0.14; p=0.002) and FACIT (B=-0.87; SE=0.30; p=0.005) and with overall work impairment were pain (B=-0.40; SE=0.11; p=0.001) and FACIT-Fatigue (B=-0.74; SE=0.28; p=0.010).Conclusion: A poor HRQoL and higher levels of fatigue were associated with a higher percentage of absenteeism, presenteeism and overall work impairment in SLE patients. Addressing the factors related to HRQoL and Fatigue may have significant impact on work performance among SLE patients.Disclosure of Interests: None declared",
author = "Sokolova, {Cristina Reategui} and {Gamboa C{\'a}rdenas}, {Roc{\'i}o Violeta} and Mariela Medina and Miranda, {Francisco Zevallos} and {Ze{\~n}a Huancas}, {Paola Alejandra} and Claudia Elera-Fitzcarrald and Quiroz, {Victor Pimentel} and Lozano, {Jose Alfaro} and Asurza, {Cesar Pastor} and Campos, {Risto Perich} and Bellido, {Zoila Rodriguez} and Alarcon, {Graciela S.} and Ugarte-Gil, {Manuel F.}",
year = "2019",
month = "6",
day = "1",
doi = "10.1136/annrheumdis-2019-eular.6564",
language = "Espa{\~n}ol (Per{\'u})",
journal = "Annals of the Rheumatic Diseases",

}

Sokolova, CR, Gamboa Cárdenas, RV, Medina, M, Miranda, FZ, Zeña Huancas, PA, Elera-Fitzcarrald, C, Quiroz, VP, Lozano, JA, Asurza, CP, Campos, RP, Bellido, ZR, Alarcon, GS & Ugarte-Gil, MF 2019, 'SAT0581 Poor health-related quality of life (hrqol) and fatigue are associated with a higher work productivity impairment in systemic lupus erythematosus (sle) patients', Annals of the Rheumatic Diseases. https://doi.org/10.1136/annrheumdis-2019-eular.6564

SAT0581 Poor health-related quality of life (hrqol) and fatigue are associated with a higher work productivity impairment in systemic lupus erythematosus (sle) patients. / Sokolova, Cristina Reategui; Gamboa Cárdenas, Rocío Violeta; Medina, Mariela; Miranda, Francisco Zevallos; Zeña Huancas, Paola Alejandra; Elera-Fitzcarrald, Claudia; Quiroz, Victor Pimentel; Lozano, Jose Alfaro; Asurza, Cesar Pastor; Campos, Risto Perich; Bellido, Zoila Rodriguez; Alarcon, Graciela S.; Ugarte-Gil, Manuel F.

En: Annals of the Rheumatic Diseases, 01.06.2019.

Resultado de la investigación: Contribución a una revistaResumen de conferenciaInvestigaciónrevisión exhaustiva

TY - JOUR

T1 - SAT0581 Poor health-related quality of life (hrqol) and fatigue are associated with a higher work productivity impairment in systemic lupus erythematosus (sle) patients

AU - Sokolova, Cristina Reategui

AU - Gamboa Cárdenas, Rocío Violeta

AU - Medina, Mariela

AU - Miranda, Francisco Zevallos

AU - Zeña Huancas, Paola Alejandra

AU - Elera-Fitzcarrald, Claudia

AU - Quiroz, Victor Pimentel

AU - Lozano, Jose Alfaro

AU - Asurza, Cesar Pastor

AU - Campos, Risto Perich

AU - Bellido, Zoila Rodriguez

AU - Alarcon, Graciela S.

AU - Ugarte-Gil, Manuel F.

PY - 2019/6/1

Y1 - 2019/6/1

N2 - Background: Because most patients with SLE are in their productive-age years, the ability to maintain a gainful employment is fundamental for both, the patient and society at large. It is thus quite important to determine the work and non-work factors that are associated with work productivity impairment in these patients.Objectives: To determine the factors associated with absenteeism (percentage of the time missed from scheduled work-time over the preceding 7 days, due to SLE), presenteeism (percentage of time from scheduled work-time where productivity was impaired while patient was at work, over the preceding 7 days, due to SLE) and overall work impairment (combination of absenteeism and presenteeism) in patients with SLE.Methods: A total of 133 consecutive (1997 American College of Rheumatology (ACR) criteria) working patients with SLE were assessed between October 2017 and December 2018, using a standardized data collection form. Sociodemographic, disease and work-related variables were collected. Disease activity was ascertained with the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI); disease damage with the Systemic Lupus International Collaborating Clinics/ACR Damage Index (SDI); health-related quality of life was assessed with the LupusQoL and fatigue with the FACIT-Fatigue (Functional Assessment of Chronic Illness Therapy-Fatigue). Work Productivity and Activity Impairment (WPAI) was assessed with the respective questionnaire; absenteeism and presenteeism due to overall health and symptoms during the past 7 days were scored. Linear regression models were performed to determine the factors associated with absenteeism, presenteeism and overall work impairment. Potential factors included were age at diagnosis, gender, socioeconomic status, educational level, SLEDAI, SDI, FACIT- Fatigue and the components of the LupusQoL.Results: The mean age at diagnosis was 32.2 years (11.8); 121 (91.7%) were female. Nearly all patients were Mestizo. Mean years of education was 14.1 (2.6). The mean disease duration was 11.9 (7.5) years. Mean SLEDAI was 2.9 (4.0), and mean SDI was 1 (1.4). The mean percent of time for absenteeism was 5.0 (12.9), it was 28.5 (26.4) for presenteeism, and it was 31.3 (27.2) for overall work impairment. In the multiple regression analysis, factors associated with absenteeism were disease duration (B=-0.34; SE=0.12; p=0.007); pain (B=-0.14; SE=0.06; p=0.046); intimate relationship (B=-0.07; SE=0.03; p=0.046) and emotional health (B=0.16; SE=0.06; p=0.006), with presenteeism were physical health (B=-0.43; SE=0.14; p=0.002) and FACIT (B=-0.87; SE=0.30; p=0.005) and with overall work impairment were pain (B=-0.40; SE=0.11; p=0.001) and FACIT-Fatigue (B=-0.74; SE=0.28; p=0.010).Conclusion: A poor HRQoL and higher levels of fatigue were associated with a higher percentage of absenteeism, presenteeism and overall work impairment in SLE patients. Addressing the factors related to HRQoL and Fatigue may have significant impact on work performance among SLE patients.Disclosure of Interests: None declared

AB - Background: Because most patients with SLE are in their productive-age years, the ability to maintain a gainful employment is fundamental for both, the patient and society at large. It is thus quite important to determine the work and non-work factors that are associated with work productivity impairment in these patients.Objectives: To determine the factors associated with absenteeism (percentage of the time missed from scheduled work-time over the preceding 7 days, due to SLE), presenteeism (percentage of time from scheduled work-time where productivity was impaired while patient was at work, over the preceding 7 days, due to SLE) and overall work impairment (combination of absenteeism and presenteeism) in patients with SLE.Methods: A total of 133 consecutive (1997 American College of Rheumatology (ACR) criteria) working patients with SLE were assessed between October 2017 and December 2018, using a standardized data collection form. Sociodemographic, disease and work-related variables were collected. Disease activity was ascertained with the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI); disease damage with the Systemic Lupus International Collaborating Clinics/ACR Damage Index (SDI); health-related quality of life was assessed with the LupusQoL and fatigue with the FACIT-Fatigue (Functional Assessment of Chronic Illness Therapy-Fatigue). Work Productivity and Activity Impairment (WPAI) was assessed with the respective questionnaire; absenteeism and presenteeism due to overall health and symptoms during the past 7 days were scored. Linear regression models were performed to determine the factors associated with absenteeism, presenteeism and overall work impairment. Potential factors included were age at diagnosis, gender, socioeconomic status, educational level, SLEDAI, SDI, FACIT- Fatigue and the components of the LupusQoL.Results: The mean age at diagnosis was 32.2 years (11.8); 121 (91.7%) were female. Nearly all patients were Mestizo. Mean years of education was 14.1 (2.6). The mean disease duration was 11.9 (7.5) years. Mean SLEDAI was 2.9 (4.0), and mean SDI was 1 (1.4). The mean percent of time for absenteeism was 5.0 (12.9), it was 28.5 (26.4) for presenteeism, and it was 31.3 (27.2) for overall work impairment. In the multiple regression analysis, factors associated with absenteeism were disease duration (B=-0.34; SE=0.12; p=0.007); pain (B=-0.14; SE=0.06; p=0.046); intimate relationship (B=-0.07; SE=0.03; p=0.046) and emotional health (B=0.16; SE=0.06; p=0.006), with presenteeism were physical health (B=-0.43; SE=0.14; p=0.002) and FACIT (B=-0.87; SE=0.30; p=0.005) and with overall work impairment were pain (B=-0.40; SE=0.11; p=0.001) and FACIT-Fatigue (B=-0.74; SE=0.28; p=0.010).Conclusion: A poor HRQoL and higher levels of fatigue were associated with a higher percentage of absenteeism, presenteeism and overall work impairment in SLE patients. Addressing the factors related to HRQoL and Fatigue may have significant impact on work performance among SLE patients.Disclosure of Interests: None declared

U2 - 10.1136/annrheumdis-2019-eular.6564

DO - 10.1136/annrheumdis-2019-eular.6564

M3 - Resumen de conferencia

JO - Annals of the Rheumatic Diseases

JF - Annals of the Rheumatic Diseases

ER -