Phylogeny of human T cell lymphotropic virus type 1 in Peru: A high degree of evolutionary relatedness with South African isolates

Gianguglielmo Zehender, Erika Ebranati, Flavia Bernini, Chiara De Maddalena, Camilla Giambelli, Jaime Collins, Ada Valverde, Zeffirino Montin, Massimo Galli

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

3 Citas (Scopus)

Resumen

We investigated the prevalence and molecular epidemiology of human T cell lymphotropic virus type 1 in Peruvian HIV-1-positive subjects, and found a 10.1% prevalence in a consecutive series of 318 HIV-1-positive patients living in Lima. Phylogenetic analysis of the long terminal repeat of 10 patient isolates showed that all of them belonged to the HTLV-1aA (Transcontinental) subgroup. Although the majority of the Peruvian sequences included in the analysis formed a clade with other Latin American sequences, the isolates of three patients clustered significantly with South African strains. These data show a high prevalence of HTLV-1 infection in HIV-1-positive subjects living in Lima and confirm the presence in Latin America of HTLV-1 strains probably arising from South Africa.

Idioma originalInglés
Páginas (desde-hasta)1146-1149
Número de páginas4
PublicaciónAIDS Research and Human Retroviruses
Volumen23
N.º9
DOI
EstadoPublicada - set. 2007
Publicado de forma externa

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