Patrones de resistencia a los antimicrobianos en serovares de salmonella enterica en Perú, 2012-2015

Willi Quino Sifuentes, Carmen V. Hurtado, Ana María Meza, María Luz Zamudio, Ronnie G. Gavilan

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

1 Cita (Scopus)

Resumen

Background: Salmonellosis is a universal zoonosis, causing frequent outbreaks of foodborne illness; Salmonella enterica is the species with the highest prevalence, a progressive increase in its resistance to antimicrobials is described. Aim: To determine the frequency of serovars and antimicrobial resistance patterns in S. enterica isolates submitted to the National Institute of Health, Lima, Peru. Methods: This is a cross-sectional study. All strains referred as part of national laboratory-based surveillance between 2012 and 2015 were included in the study. Strains were confirmed by conventional tests and serotyped by the Kauffmann-White scheme; antimicrobial susceptibility and confirmation of the BLEE phenotype was performed according to the method of Kirby-Bauer and Jarlier’s method. Results: A total of 540 strains of S. enterica were included in the study, where 96% (520/540) corresponded to human strains and 4% (20/540) to non-human strains (birds, food and environmental). In human samples, the most frequent serovar was S. Infantis (57%), followed by S. Enteritidis (27%) and S. Typhimurium (6%). High resistance to nitrofurantoin (74%), nali-dixic acid (64%), ciprofloxacin (63%), tetracycline (63%), ampicillin (56%), sulfamethoxazole-trimethoprim (56%), cefotaxime (53%) and chloramphenicol (50%) was detected. In non-human samples, the most frequent serotype was S. Infantis (45%), followed by S. Typhimurium (40%) and S. Enteritidis (10%); a high resistance to nalidixic acid (55%), ciprofloxacin (45%), sulfamethoxazole-trimethoprim (40%), nitrofurantoin (40%), tetracycline (40%) was found. 65% of all strains had resistance to more than two antibiotics, 43,3% were ESBL producers and 99% of these had resistance between six and eight antibiotics. Conclusions: We found a high frequency of S. Infantis producing ESBL with multi-resistance to the antimicrobials in human and nonhuman samples received by the National Institute of Health.

Título traducido de la contribuciónPatterns of resistance to antimicrobials in serovars of salmonella enterica in Peru, 2012-2015
Idioma originalEspañol
Páginas (desde-hasta)395-401
Número de páginas7
PublicaciónRevista Chilena de Infectologia
Volumen37
N.º4
DOI
EstadoPublicada - ago 2020
Publicado de forma externa

Palabras clave

  • Antibiotic resistance
  • Salmonella
  • β-lactamase

Huella

Profundice en los temas de investigación de 'Patrones de resistencia a los antimicrobianos en serovares de salmonella enterica en Perú, 2012-2015'. En conjunto forman una huella única.

Citar esto