Menopausal symptoms appear before the menopause and persist 5 years beyond: A detailed analysis of a multinational study

J. E. Blümel, P. Chedraui, G. Baron, E. Belzares, A. Bencosme, A. Calle, L. Danckers, M. T. Espinoza, D. Flores, G. Gomez, J. A. Hernandez-Bueno, H. Izaguirre, P. Leon-Leon, S. Lima, E. Mezones-Holguin, A. Monterrosa, D. Mostajo, D. Navarro, E. Ojeda, W. Onatra & 4 otros M. Royer, E. Soto, K. Tserotas, M. S. Vallejo

Resultado de la investigación: Contribución a una revistaArtículoInvestigaciónrevisión exhaustiva

31 Citas (Scopus)

Resumen

Objective Few Latin American studies have described menopausal symptoms in detail by means of a standardized assessment tool. The objective of this study was to assess the prevalence and severity of menopausal symptoms and their impact over quality of life among mid-aged Latin American women. Method In this cross-sectional study, 8373 otherwise healthy women aged 40-59 years from 12 Latin American countries were asked to fill out the Menopause Rating Scale (MRS) and a questionnaire containing personal sociodemographic data. Menopause status (pre-, peri- and postmenopausal) was defined according to the criteria of the Stages of Reproductive Aging Workshop. Results Of all the studied women, 90.9% had at least one menopausal symptom (complaint) that they rated. Muscle and joint discomfort, physical and mental exhaustion and depressive mood were highly prevalent and rated as severe-very severe (scores of 3 and 4), at a higher rate than vasomotor symptoms (15.6%, 13.8% and 13.7% vs. 9.6%, respectively). Of premenopausal women (40-44 years), 77.0% reported at least one rated complaint, with 12.9% displaying MRS scores defined as severe (>16). The latter rate increased to 26.4% in perimenopausal, 31.6% in early postmenopausal and 29.9% among late postmenopausal women. As measured with the MRS, the presence of hot flushes increased the risk of impairment of overall quality of life in both premenopausal (odds ratio 12.67; 95% confidence interval 9.53=16.83) and peri/postmenopausal women (odds ratio 9.37; 95% confidence interval 7.85=11.19). Conclusion In this large, mid-aged, female Latin American series, muscle/joint discomfort and psychological symptoms were the most prevalent and severely rated menopausal symptoms. The symptoms appear early in the premenopause, significantly impair quality of life and persist 5 years beyond the menopause. © 2012 International Menopause Society.
Idioma originalInglés estadounidense
Páginas (desde-hasta)542-551
Número de páginas10
PublicaciónClimacteric
DOI
EstadoPublicada - 1 dic 2012
Publicado de forma externa

Huella dactilar

Menopause
Quality of Life
Joints
Premenopause
Odds Ratio
Confidence Intervals
Muscles
Cross-Sectional Studies
Psychology
Education

Citar esto

Blümel, J. E., Chedraui, P., Baron, G., Belzares, E., Bencosme, A., Calle, A., ... Vallejo, M. S. (2012). Menopausal symptoms appear before the menopause and persist 5 years beyond: A detailed analysis of a multinational study. Climacteric, 542-551. https://doi.org/10.3109/13697137.2012.658462
Blümel, J. E. ; Chedraui, P. ; Baron, G. ; Belzares, E. ; Bencosme, A. ; Calle, A. ; Danckers, L. ; Espinoza, M. T. ; Flores, D. ; Gomez, G. ; Hernandez-Bueno, J. A. ; Izaguirre, H. ; Leon-Leon, P. ; Lima, S. ; Mezones-Holguin, E. ; Monterrosa, A. ; Mostajo, D. ; Navarro, D. ; Ojeda, E. ; Onatra, W. ; Royer, M. ; Soto, E. ; Tserotas, K. ; Vallejo, M. S. / Menopausal symptoms appear before the menopause and persist 5 years beyond: A detailed analysis of a multinational study. En: Climacteric. 2012 ; pp. 542-551.
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title = "Menopausal symptoms appear before the menopause and persist 5 years beyond: A detailed analysis of a multinational study",
abstract = "Objective Few Latin American studies have described menopausal symptoms in detail by means of a standardized assessment tool. The objective of this study was to assess the prevalence and severity of menopausal symptoms and their impact over quality of life among mid-aged Latin American women. Method In this cross-sectional study, 8373 otherwise healthy women aged 40-59 years from 12 Latin American countries were asked to fill out the Menopause Rating Scale (MRS) and a questionnaire containing personal sociodemographic data. Menopause status (pre-, peri- and postmenopausal) was defined according to the criteria of the Stages of Reproductive Aging Workshop. Results Of all the studied women, 90.9{\%} had at least one menopausal symptom (complaint) that they rated. Muscle and joint discomfort, physical and mental exhaustion and depressive mood were highly prevalent and rated as severe-very severe (scores of 3 and 4), at a higher rate than vasomotor symptoms (15.6{\%}, 13.8{\%} and 13.7{\%} vs. 9.6{\%}, respectively). Of premenopausal women (40-44 years), 77.0{\%} reported at least one rated complaint, with 12.9{\%} displaying MRS scores defined as severe (>16). The latter rate increased to 26.4{\%} in perimenopausal, 31.6{\%} in early postmenopausal and 29.9{\%} among late postmenopausal women. As measured with the MRS, the presence of hot flushes increased the risk of impairment of overall quality of life in both premenopausal (odds ratio 12.67; 95{\%} confidence interval 9.53=16.83) and peri/postmenopausal women (odds ratio 9.37; 95{\%} confidence interval 7.85=11.19). Conclusion In this large, mid-aged, female Latin American series, muscle/joint discomfort and psychological symptoms were the most prevalent and severely rated menopausal symptoms. The symptoms appear early in the premenopause, significantly impair quality of life and persist 5 years beyond the menopause. {\circledC} 2012 International Menopause Society.",
author = "Bl{\"u}mel, {J. E.} and P. Chedraui and G. Baron and E. Belzares and A. Bencosme and A. Calle and L. Danckers and Espinoza, {M. T.} and D. Flores and G. Gomez and Hernandez-Bueno, {J. A.} and H. Izaguirre and P. Leon-Leon and S. Lima and E. Mezones-Holguin and A. Monterrosa and D. Mostajo and D. Navarro and E. Ojeda and W. Onatra and M. Royer and E. Soto and K. Tserotas and Vallejo, {M. S.}",
year = "2012",
month = "12",
day = "1",
doi = "10.3109/13697137.2012.658462",
language = "American English",
pages = "542--551",
journal = "Climacteric",
issn = "1369-7137",
publisher = "Taylor & Francis",

}

Blümel, JE, Chedraui, P, Baron, G, Belzares, E, Bencosme, A, Calle, A, Danckers, L, Espinoza, MT, Flores, D, Gomez, G, Hernandez-Bueno, JA, Izaguirre, H, Leon-Leon, P, Lima, S, Mezones-Holguin, E, Monterrosa, A, Mostajo, D, Navarro, D, Ojeda, E, Onatra, W, Royer, M, Soto, E, Tserotas, K & Vallejo, MS 2012, 'Menopausal symptoms appear before the menopause and persist 5 years beyond: A detailed analysis of a multinational study', Climacteric, pp. 542-551. https://doi.org/10.3109/13697137.2012.658462

Menopausal symptoms appear before the menopause and persist 5 years beyond: A detailed analysis of a multinational study. / Blümel, J. E.; Chedraui, P.; Baron, G.; Belzares, E.; Bencosme, A.; Calle, A.; Danckers, L.; Espinoza, M. T.; Flores, D.; Gomez, G.; Hernandez-Bueno, J. A.; Izaguirre, H.; Leon-Leon, P.; Lima, S.; Mezones-Holguin, E.; Monterrosa, A.; Mostajo, D.; Navarro, D.; Ojeda, E.; Onatra, W.; Royer, M.; Soto, E.; Tserotas, K.; Vallejo, M. S.

En: Climacteric, 01.12.2012, p. 542-551.

Resultado de la investigación: Contribución a una revistaArtículoInvestigaciónrevisión exhaustiva

TY - JOUR

T1 - Menopausal symptoms appear before the menopause and persist 5 years beyond: A detailed analysis of a multinational study

AU - Blümel, J. E.

AU - Chedraui, P.

AU - Baron, G.

AU - Belzares, E.

AU - Bencosme, A.

AU - Calle, A.

AU - Danckers, L.

AU - Espinoza, M. T.

AU - Flores, D.

AU - Gomez, G.

AU - Hernandez-Bueno, J. A.

AU - Izaguirre, H.

AU - Leon-Leon, P.

AU - Lima, S.

AU - Mezones-Holguin, E.

AU - Monterrosa, A.

AU - Mostajo, D.

AU - Navarro, D.

AU - Ojeda, E.

AU - Onatra, W.

AU - Royer, M.

AU - Soto, E.

AU - Tserotas, K.

AU - Vallejo, M. S.

PY - 2012/12/1

Y1 - 2012/12/1

N2 - Objective Few Latin American studies have described menopausal symptoms in detail by means of a standardized assessment tool. The objective of this study was to assess the prevalence and severity of menopausal symptoms and their impact over quality of life among mid-aged Latin American women. Method In this cross-sectional study, 8373 otherwise healthy women aged 40-59 years from 12 Latin American countries were asked to fill out the Menopause Rating Scale (MRS) and a questionnaire containing personal sociodemographic data. Menopause status (pre-, peri- and postmenopausal) was defined according to the criteria of the Stages of Reproductive Aging Workshop. Results Of all the studied women, 90.9% had at least one menopausal symptom (complaint) that they rated. Muscle and joint discomfort, physical and mental exhaustion and depressive mood were highly prevalent and rated as severe-very severe (scores of 3 and 4), at a higher rate than vasomotor symptoms (15.6%, 13.8% and 13.7% vs. 9.6%, respectively). Of premenopausal women (40-44 years), 77.0% reported at least one rated complaint, with 12.9% displaying MRS scores defined as severe (>16). The latter rate increased to 26.4% in perimenopausal, 31.6% in early postmenopausal and 29.9% among late postmenopausal women. As measured with the MRS, the presence of hot flushes increased the risk of impairment of overall quality of life in both premenopausal (odds ratio 12.67; 95% confidence interval 9.53=16.83) and peri/postmenopausal women (odds ratio 9.37; 95% confidence interval 7.85=11.19). Conclusion In this large, mid-aged, female Latin American series, muscle/joint discomfort and psychological symptoms were the most prevalent and severely rated menopausal symptoms. The symptoms appear early in the premenopause, significantly impair quality of life and persist 5 years beyond the menopause. © 2012 International Menopause Society.

AB - Objective Few Latin American studies have described menopausal symptoms in detail by means of a standardized assessment tool. The objective of this study was to assess the prevalence and severity of menopausal symptoms and their impact over quality of life among mid-aged Latin American women. Method In this cross-sectional study, 8373 otherwise healthy women aged 40-59 years from 12 Latin American countries were asked to fill out the Menopause Rating Scale (MRS) and a questionnaire containing personal sociodemographic data. Menopause status (pre-, peri- and postmenopausal) was defined according to the criteria of the Stages of Reproductive Aging Workshop. Results Of all the studied women, 90.9% had at least one menopausal symptom (complaint) that they rated. Muscle and joint discomfort, physical and mental exhaustion and depressive mood were highly prevalent and rated as severe-very severe (scores of 3 and 4), at a higher rate than vasomotor symptoms (15.6%, 13.8% and 13.7% vs. 9.6%, respectively). Of premenopausal women (40-44 years), 77.0% reported at least one rated complaint, with 12.9% displaying MRS scores defined as severe (>16). The latter rate increased to 26.4% in perimenopausal, 31.6% in early postmenopausal and 29.9% among late postmenopausal women. As measured with the MRS, the presence of hot flushes increased the risk of impairment of overall quality of life in both premenopausal (odds ratio 12.67; 95% confidence interval 9.53=16.83) and peri/postmenopausal women (odds ratio 9.37; 95% confidence interval 7.85=11.19). Conclusion In this large, mid-aged, female Latin American series, muscle/joint discomfort and psychological symptoms were the most prevalent and severely rated menopausal symptoms. The symptoms appear early in the premenopause, significantly impair quality of life and persist 5 years beyond the menopause. © 2012 International Menopause Society.

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