Los Estudios De Síntesis Como Base Para Las Evaluaciones Económicas: Necesidad De La Valoración De Su Calidad

Rafael Bolaños-Díaz, Edward Mezones Holguin, Alfonso Gutiérrez-Aguado, Germán Málaga

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

2 Citas (Scopus)

Resumen

Synthesis studies (SS): systematic review and meta-analysis are the basis for developing Health Economic Evaluations (HEE). SS allow us to obtain parameters for estimating probabilities and effectiveness from the combination of the results of primary studies, and, as they include in their methodology the selection, evaluation, systematization and synthesis processes, they are considered the first level of hierarchy in scientific evidence. Nevertheless, they can be prone to bias and methodological failures that can affect the validity of their results. This article initially presents the relevance of the randomization in the hierarchic classification of research designs, then it reviews the main factors affecting the validity of the SS, emphasising the publication bias, the heterogeneity and the inclusion of primary studies with main objective differing from the one of the SS. Moreover, it presents individual studies like a valid alternative for the development of a SS. The conclusion is that one of the key aspects in a SS is the correct evaluation of the study types and the objective evaluation of their quality, being these primary or secondary.

Título traducido de la contribuciónSynthesis studies as the basis for economic evaluations in health: The need for their quality appraisal
Idioma originalEspañol
Páginas (desde-hasta)528-534
Número de páginas7
PublicaciónRevista Peruana de Medicina Experimental y Salud Publica
Volumen28
N.º3
DOI
EstadoPublicada - 2011
Publicado de forma externa

Palabras clave

  • Evidence-based practice
  • Health economics (source: MeSH NLM)
  • Health Research research evaluation
  • Meta-analysis as topic
  • Reviews

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