In-hospital mortality among incident hemodialysis older patients in Peru

Percy Herrera-Añazco, Pedro J Ortiz, Jesus E Peinado, Tania Tello, Fabiola Valero, Adrian V Hernandez, J Jaime Miranda

Resultado de la investigación: Contribución a una revistaArtículoInvestigaciónrevisión exhaustiva

Resumen

BACKGROUND: Understanding the pattern of mortality linked to end stage renal disease (ESRD) is important given the increasing ageing population in low- and middle-income countries.

METHODS: We analyzed older patients with ESRD with incident hemodialysis, from January 2012 to August 2017 in one large general hospital in Peru. Individual and health system-related variables were analyzed using Generalized Linear Models (GLM) to estimate their association with in-hospital all-cause mortality. Relative risk (RR) with their 95% confidence intervals (95% CI) were calculated.

RESULTS: We evaluated 312 patients; mean age 69 years, 93.6% started hemodialysis with a transient central venous catheter, 1.7% had previous hemodialysis indication and 24.7% died during hospital stay. The mean length of stay was 16.1 days (SD 13.5). In the adjusted multivariate models, we found higher in-hospital mortality among those with encephalopathy (aRR 1.85, 95% CI 1.21-2.82 vs. without encephalopathy) and a lower in-hospital mortality among those with eGFR ≤7 mL/min (aRR 0.45, 95% CI 0.31-0.67 vs. eGFR>7 mL/min).

CONCLUSIONS: There is a high in-hospital mortality among older hemodialysis patients in Peru. The presence of uremic encephalopathy was associated with higher mortality and a lower estimated glomerular filtration rate with lower mortality.

Idioma originalInglés
PublicaciónPublic Health
DOI
EstadoPublicación electrónica previa a su impresión - 11 jul 2019

Huella dactilar

Peru
Hospital Mortality
Renal Dialysis
Brain Diseases
Mortality
Confidence Intervals
Chronic Kidney Failure
Length of Stay
Central Venous Catheters
Glomerular Filtration Rate
General Hospitals
Linear Models
Health
Population

Citar esto

Herrera-Añazco, Percy ; Ortiz, Pedro J ; Peinado, Jesus E ; Tello, Tania ; Valero, Fabiola ; Hernandez, Adrian V ; Miranda, J Jaime. / In-hospital mortality among incident hemodialysis older patients in Peru. En: Public Health. 2019.
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title = "In-hospital mortality among incident hemodialysis older patients in Peru",
abstract = "BACKGROUND: Understanding the pattern of mortality linked to end stage renal disease (ESRD) is important given the increasing ageing population in low- and middle-income countries.METHODS: We analyzed older patients with ESRD with incident hemodialysis, from January 2012 to August 2017 in one large general hospital in Peru. Individual and health system-related variables were analyzed using Generalized Linear Models (GLM) to estimate their association with in-hospital all-cause mortality. Relative risk (RR) with their 95{\%} confidence intervals (95{\%} CI) were calculated.RESULTS: We evaluated 312 patients; mean age 69 years, 93.6{\%} started hemodialysis with a transient central venous catheter, 1.7{\%} had previous hemodialysis indication and 24.7{\%} died during hospital stay. The mean length of stay was 16.1 days (SD 13.5). In the adjusted multivariate models, we found higher in-hospital mortality among those with encephalopathy (aRR 1.85, 95{\%} CI 1.21-2.82 vs. without encephalopathy) and a lower in-hospital mortality among those with eGFR ≤7 mL/min (aRR 0.45, 95{\%} CI 0.31-0.67 vs. eGFR>7 mL/min).CONCLUSIONS: There is a high in-hospital mortality among older hemodialysis patients in Peru. The presence of uremic encephalopathy was associated with higher mortality and a lower estimated glomerular filtration rate with lower mortality.",
author = "Percy Herrera-A{\~n}azco and Ortiz, {Pedro J} and Peinado, {Jesus E} and Tania Tello and Fabiola Valero and Hernandez, {Adrian V} and Miranda, {J Jaime}",
note = "{\circledC} The Author(s) 2019. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.",
year = "2019",
month = "7",
day = "11",
doi = "10.1093/inthealth/ihz037",
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In-hospital mortality among incident hemodialysis older patients in Peru. / Herrera-Añazco, Percy; Ortiz, Pedro J; Peinado, Jesus E; Tello, Tania; Valero, Fabiola; Hernandez, Adrian V; Miranda, J Jaime.

En: Public Health, 11.07.2019.

Resultado de la investigación: Contribución a una revistaArtículoInvestigaciónrevisión exhaustiva

TY - JOUR

T1 - In-hospital mortality among incident hemodialysis older patients in Peru

AU - Herrera-Añazco, Percy

AU - Ortiz, Pedro J

AU - Peinado, Jesus E

AU - Tello, Tania

AU - Valero, Fabiola

AU - Hernandez, Adrian V

AU - Miranda, J Jaime

N1 - © The Author(s) 2019. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

PY - 2019/7/11

Y1 - 2019/7/11

N2 - BACKGROUND: Understanding the pattern of mortality linked to end stage renal disease (ESRD) is important given the increasing ageing population in low- and middle-income countries.METHODS: We analyzed older patients with ESRD with incident hemodialysis, from January 2012 to August 2017 in one large general hospital in Peru. Individual and health system-related variables were analyzed using Generalized Linear Models (GLM) to estimate their association with in-hospital all-cause mortality. Relative risk (RR) with their 95% confidence intervals (95% CI) were calculated.RESULTS: We evaluated 312 patients; mean age 69 years, 93.6% started hemodialysis with a transient central venous catheter, 1.7% had previous hemodialysis indication and 24.7% died during hospital stay. The mean length of stay was 16.1 days (SD 13.5). In the adjusted multivariate models, we found higher in-hospital mortality among those with encephalopathy (aRR 1.85, 95% CI 1.21-2.82 vs. without encephalopathy) and a lower in-hospital mortality among those with eGFR ≤7 mL/min (aRR 0.45, 95% CI 0.31-0.67 vs. eGFR>7 mL/min).CONCLUSIONS: There is a high in-hospital mortality among older hemodialysis patients in Peru. The presence of uremic encephalopathy was associated with higher mortality and a lower estimated glomerular filtration rate with lower mortality.

AB - BACKGROUND: Understanding the pattern of mortality linked to end stage renal disease (ESRD) is important given the increasing ageing population in low- and middle-income countries.METHODS: We analyzed older patients with ESRD with incident hemodialysis, from January 2012 to August 2017 in one large general hospital in Peru. Individual and health system-related variables were analyzed using Generalized Linear Models (GLM) to estimate their association with in-hospital all-cause mortality. Relative risk (RR) with their 95% confidence intervals (95% CI) were calculated.RESULTS: We evaluated 312 patients; mean age 69 years, 93.6% started hemodialysis with a transient central venous catheter, 1.7% had previous hemodialysis indication and 24.7% died during hospital stay. The mean length of stay was 16.1 days (SD 13.5). In the adjusted multivariate models, we found higher in-hospital mortality among those with encephalopathy (aRR 1.85, 95% CI 1.21-2.82 vs. without encephalopathy) and a lower in-hospital mortality among those with eGFR ≤7 mL/min (aRR 0.45, 95% CI 0.31-0.67 vs. eGFR>7 mL/min).CONCLUSIONS: There is a high in-hospital mortality among older hemodialysis patients in Peru. The presence of uremic encephalopathy was associated with higher mortality and a lower estimated glomerular filtration rate with lower mortality.

U2 - 10.1093/inthealth/ihz037

DO - 10.1093/inthealth/ihz037

M3 - Artículo

JO - Public Health

JF - Public Health

SN - 0033-3506

ER -