Guía de práctica clínica para el tratamiento del cáncer de próstata metastásico hormonosensible en el Seguro Social del Perú (EsSalud)

Nelson Cuevas-Muñoz, Oswaldo Broncano-Huasasquiche, Sergio Goicochea-Lugo, Carolina J. Delgado-Flores, Alvaro Taype-Rondan, Eliana L. Fernandez-Quiroz, Teofilo Livano Yberico, Mariano Cuentas-Jara, Abel Cordier-Mariaca, Luís Alberto Velarde-Ponce, Jesús Delgado-Iriarte, Vladimir Santos-Sánchez*, Stefany Salvador-Salvador

*Autor correspondiente de este trabajo

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

Resumen

Introduction: This article summarizes the clinical practice guideline (CPG) for the treatment of metastatic hormone-sensitive prostate cancer in the Social Security of Peru (EsSalud). Objective: To provide evidence-based clinical recommendations for the treatment of adults with hormone-sensitive metastatic adenocarcinoma of the prostate with de novo or recurrent presentation and high or low metastatic volume in EsSalud. Methods: A guideline development group (GDG) was formed, which included specialist physicians and methodologists, who formulated clinical questions. Systematic searches were conducted for systematic reviews and - when deemed relevant - primary studies in PubMed during 2022. Evidence was selected to answer each of the clinical questions posed. The certainty of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology. In periodic working meetings, the GEG used the GRADE methodology to review the evidence and formulate recommendations. The CPG was reviewed by external experts before its approval. Results: The CPG addressed 6 clinical questions, divided into 2 main topics: considerations on androgen deprivation therapy (ADT) and ADT combined with other therapies. Based on these questions, 10 recommendations were formulated (4 strong and 6 conditional), and 6 points of good clinical practice. Conclusion: Evidence-based recommendations were issued for the management of patients with this pathology.

Título traducido de la contribuciónClinical practice guideline for the treatment of hormone-sensitive metastatic prostate cancer in the Peruvian Social Security (EsSalud)
Idioma originalEspañol
PublicaciónRevista del Cuerpo Medico Hospital Nacional Almanzor Aguinaga Asenjo
Volumen16
N.º4
DOI
EstadoPublicada - 2023

Palabras clave

  • Evidence-Based Medicine. (MeSH – NLM)
  • GRADE Approach
  • Neoplasm Metastasis
  • Practice Guidelines as Topic
  • Prostatic Neoplasms

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