Factors associated with mortality in a population with acute kidney injury undergoing hemodialysis in Peru

Resultado de la investigación: Contribución a una revistaArtículoInvestigaciónrevisión exhaustiva

Resumen

INTRODUCTION: Patients with acute kidney injury (AKI) in developing countries are described in a profile of young age, with less comorbidities, with unifactorial, and with a lower mortality compared to patients in developed countries.OBJECTIVE: To assess mortality in patients with acute kidney injury undergoing hemodialysis (HD) and its associated factors in a developing country setting.METHODS: Retrospective study. Demographic, clinical, and mortality variables were collected from patients who presented AKI and underwent HD between January 2014 and December 2015 at a national reference hospital in Lima, Peru. Risk ratios (RR) and 95% confidence intervals (95%CI) were estimated through Poisson regressions.RESULTS: Data from 72 patients with AKI that underwent HD were analyzed, 66.7% of them were < 64 years old, and 40.2% of all patients died undergoing HD. Crude analysis showed higher mortality among those who used vasopressors, but lower mortality among those with creatinine values > 8.9 mg/dL. The adjusted analysis showed that having had a creatinine level of > 8.9 mg/dL, compared to a creatinine level of < 5.2 mg/dL at the time of initiating HD, was associated with 74% less probability of death.CONCLUSION: Four out of every ten AKI patients undergoing HD die. Higher levels of creatinine were associated with lower probability of mortality.
Idioma originalInglés estadounidense
Páginas (desde-hasta)119-125
Número de páginas7
PublicaciónJornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
DOI
EstadoPublicada - 1 abr 2017

Huella dactilar

Peru
Acute Kidney Injury
Developing countries
Renal Dialysis
Creatinine
Mortality
Population
Developing Countries
Developed Countries
Comorbidity
Retrospective Studies
Odds Ratio
Demography
Confidence Intervals

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title = "Factors associated with mortality in a population with acute kidney injury undergoing hemodialysis in Peru",
abstract = "INTRODUCTION: Patients with acute kidney injury (AKI) in developing countries are described in a profile of young age, with less comorbidities, with unifactorial, and with a lower mortality compared to patients in developed countries.OBJECTIVE: To assess mortality in patients with acute kidney injury undergoing hemodialysis (HD) and its associated factors in a developing country setting.METHODS: Retrospective study. Demographic, clinical, and mortality variables were collected from patients who presented AKI and underwent HD between January 2014 and December 2015 at a national reference hospital in Lima, Peru. Risk ratios (RR) and 95{\%} confidence intervals (95{\%}CI) were estimated through Poisson regressions.RESULTS: Data from 72 patients with AKI that underwent HD were analyzed, 66.7{\%} of them were < 64 years old, and 40.2{\%} of all patients died undergoing HD. Crude analysis showed higher mortality among those who used vasopressors, but lower mortality among those with creatinine values > 8.9 mg/dL. The adjusted analysis showed that having had a creatinine level of > 8.9 mg/dL, compared to a creatinine level of < 5.2 mg/dL at the time of initiating HD, was associated with 74{\%} less probability of death.CONCLUSION: Four out of every ten AKI patients undergoing HD die. Higher levels of creatinine were associated with lower probability of mortality.",
author = "Percy Herrera-A{\~n}azco and Alvaro Taype-Rondan and Josmel Pacheco-Mendoza and Miranda, {J. Jaime}",
year = "2017",
month = "4",
day = "1",
doi = "10.5935/0101-2800.20170029",
language = "American English",
pages = "119--125",
journal = "Jornal brasileiro de nefrologia : orgão oficial de Sociedades Brasileira e Latino-Americana de Nefrologia",
issn = "2175-8239",
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T1 - Factors associated with mortality in a population with acute kidney injury undergoing hemodialysis in Peru

AU - Herrera-Añazco, Percy

AU - Taype-Rondan, Alvaro

AU - Pacheco-Mendoza, Josmel

AU - Miranda, J. Jaime

PY - 2017/4/1

Y1 - 2017/4/1

N2 - INTRODUCTION: Patients with acute kidney injury (AKI) in developing countries are described in a profile of young age, with less comorbidities, with unifactorial, and with a lower mortality compared to patients in developed countries.OBJECTIVE: To assess mortality in patients with acute kidney injury undergoing hemodialysis (HD) and its associated factors in a developing country setting.METHODS: Retrospective study. Demographic, clinical, and mortality variables were collected from patients who presented AKI and underwent HD between January 2014 and December 2015 at a national reference hospital in Lima, Peru. Risk ratios (RR) and 95% confidence intervals (95%CI) were estimated through Poisson regressions.RESULTS: Data from 72 patients with AKI that underwent HD were analyzed, 66.7% of them were < 64 years old, and 40.2% of all patients died undergoing HD. Crude analysis showed higher mortality among those who used vasopressors, but lower mortality among those with creatinine values > 8.9 mg/dL. The adjusted analysis showed that having had a creatinine level of > 8.9 mg/dL, compared to a creatinine level of < 5.2 mg/dL at the time of initiating HD, was associated with 74% less probability of death.CONCLUSION: Four out of every ten AKI patients undergoing HD die. Higher levels of creatinine were associated with lower probability of mortality.

AB - INTRODUCTION: Patients with acute kidney injury (AKI) in developing countries are described in a profile of young age, with less comorbidities, with unifactorial, and with a lower mortality compared to patients in developed countries.OBJECTIVE: To assess mortality in patients with acute kidney injury undergoing hemodialysis (HD) and its associated factors in a developing country setting.METHODS: Retrospective study. Demographic, clinical, and mortality variables were collected from patients who presented AKI and underwent HD between January 2014 and December 2015 at a national reference hospital in Lima, Peru. Risk ratios (RR) and 95% confidence intervals (95%CI) were estimated through Poisson regressions.RESULTS: Data from 72 patients with AKI that underwent HD were analyzed, 66.7% of them were < 64 years old, and 40.2% of all patients died undergoing HD. Crude analysis showed higher mortality among those who used vasopressors, but lower mortality among those with creatinine values > 8.9 mg/dL. The adjusted analysis showed that having had a creatinine level of > 8.9 mg/dL, compared to a creatinine level of < 5.2 mg/dL at the time of initiating HD, was associated with 74% less probability of death.CONCLUSION: Four out of every ten AKI patients undergoing HD die. Higher levels of creatinine were associated with lower probability of mortality.

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