Factores asociados a la muerte por covid-19 en pacientes admitidos en un hospital pÚblico en Tacna, PerÚ

Miguel Hueda-Zavaleta, Cesar Copaja-Corzo, Fabrizzio Bardales-Silva, Rodrigo Flores-Palacios, Luis Barreto-Rocchetti, Vicente A. Benites-Zapata

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

1 Cita (Scopus)

Resumen

Objective: To describe the clinical, laboratory and treatment characteristics of COVID-19 patients and to determine the factors associated with mortality during hospital stay. Materials and Methods: Retrospective cohort study of adult COVID-19 inpatients. The clinical, laboratory and treatment data were obtained from the medical records of patients from the Hospital Nivel III Daniel Alcides Carrión in Tacna. For the survival analysis we used the Cox proportional hazards model, and we calculated crude and adjusted hazard ratios (HR) with 95% confidence intervals (95% CI). Results: We evaluated 351 patients; 74.1% of them were men. The most common comorbidities were obesity (31.6%), hypertension (27.1%) and diabetes mellitus (24.5%). The median time of hospitalization was 8 days (IQR: 4-15). From the total of patients, 32.9% died during follow-up. The multivariate analysis showed an increased risk of dying associated with the following: Age ≥65 years, HR = 3.55 (95% CI: 1.70-7.40); increase in lactate dehydrogenase >720 U/L, HR = 2.08 (95% CI: 1.34-3.22); and oxygen saturation less than 90%, mainly when it was less than 80%, HR = 4.07 (95% CI: 2.10-7.88). In addition, the use of colchicine during treatment showed a protective effect, HR = 0.46 (95% CI: 0.23-0.91). Conclusions: Risk factors for mortality due to COVID-19 included being older than 65 years, having oxygen saturation less than 90%, and elevated lactate dehydrogenase >720 U/L; colchicine treatment could improve the prognosis of patients.

Título traducido de la contribuciónFactors associated with mortality due to COVID-19 in patients from a public hospital in Tacna, Peru
Idioma originalEspañol
Páginas (desde-hasta)214-223
Número de páginas10
PublicaciónRevista Peruana de Medicina Experimental y Salud Publica
Volumen38
N.º2
DOI
EstadoPublicada - 1 abr 2021

Palabras clave

  • Coronavirus Infections
  • COVID-19
  • Hospitalization
  • Mortality
  • Pandemics
  • Peru. (Source: MeSH NLM)
  • Risk Factors
  • SARS-CoV-2
  • Survival
  • Viral Pneumonia

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