TY - JOUR
T1 - Diagnostic accuracy of brief cognitive screening tools to diagnose vascular cognitive impairment in Peru
AU - Custodio, Nilton
AU - Montesinos, Rosa
AU - Alva-Diaz, Carlos
AU - Pacheco Barrios, Kevin Arturo
AU - Rodriguez-Calienes, Aaron
AU - Herrera-Pérez, Eder
AU - Becerra-Becerra, Yahaira
AU - Castro-Suárez, Sheila
AU - Pintado-Caipa, Maritza
AU - Cruz del Castillo, Rossana
AU - Cuenca, José
AU - Lira, David
N1 - Publisher Copyright:
© 2021 John Wiley & Sons Ltd.
PY - 2022/1/1
Y1 - 2022/1/1
N2 - Introduction: To evaluate the diagnostic accuracy of three brief cognitive screening (BCS) tools, Peruvian version of Addenbrooke's Cognitive Examination (ACE-Pe), of INECO Frontal Screening (IFS-Pe) and of the Mini-Mental State Examination (MMSE-Pe), for the diagnosis of vascular cognitive impairment (VCI) and its non-dementia stages (VCI-ND) and vascular dementia (VD) in patients with cerebral stroke in Lima—Peru. Materials and methods: A cohort analysis to evaluate the diagnostic accuracy of three BCS for VCI. Results: Two hundred and four patients were evaluated: 61% Non-VCI, 30% VCI-ND and 9% VD. To discriminate patients with VCI from controls, the area under the curve (AUC) of ACE-Pe, IFS-Pe and MMs-Pe were 0.99 (95% confidence interval [CI] 0.98–0.99), 0.99 (95%CI 0.98–0.99) and 0.87 (95%CI 0.82–0.92), respectively. Of the three BCS, the IFS-Pe presented a larger AUC to discriminate VCI-ND from VD (AUC = 0.98 [95%CI 0.95–1]) compared to ACE-Pe (AUC = 0.84 [95%CI 0.74–0.95]) and MMSE-Pe (0.92 [95%CI 0.86–0.99]). The IFS-Pe presented a higher sensitivity (S), specificity (Sp), and positive (+LR) and negative likelihood ratios (−LR) (S = 96.72%, Sp = 89.47%, +LR = 9.1 and −LR = 0.03) than ACE-Pe (S = 96.72%, Sp = 63.16%, +LR = 2.62 and −LR = 0.05) and MMSE-Pe (S = 90.16%, Sp = 78.95%, +LR = 4.28 and −LR = 0.12). In the multiple regression analysis, the IFS-Pe was not affected by age, sex or years of schooling. Conclusion: The IFS-Pe has the best diagnostic accuracy for detecting VCI and discriminating between pre-dementia (VCI-ND) and dementia (VD) stages.
AB - Introduction: To evaluate the diagnostic accuracy of three brief cognitive screening (BCS) tools, Peruvian version of Addenbrooke's Cognitive Examination (ACE-Pe), of INECO Frontal Screening (IFS-Pe) and of the Mini-Mental State Examination (MMSE-Pe), for the diagnosis of vascular cognitive impairment (VCI) and its non-dementia stages (VCI-ND) and vascular dementia (VD) in patients with cerebral stroke in Lima—Peru. Materials and methods: A cohort analysis to evaluate the diagnostic accuracy of three BCS for VCI. Results: Two hundred and four patients were evaluated: 61% Non-VCI, 30% VCI-ND and 9% VD. To discriminate patients with VCI from controls, the area under the curve (AUC) of ACE-Pe, IFS-Pe and MMs-Pe were 0.99 (95% confidence interval [CI] 0.98–0.99), 0.99 (95%CI 0.98–0.99) and 0.87 (95%CI 0.82–0.92), respectively. Of the three BCS, the IFS-Pe presented a larger AUC to discriminate VCI-ND from VD (AUC = 0.98 [95%CI 0.95–1]) compared to ACE-Pe (AUC = 0.84 [95%CI 0.74–0.95]) and MMSE-Pe (0.92 [95%CI 0.86–0.99]). The IFS-Pe presented a higher sensitivity (S), specificity (Sp), and positive (+LR) and negative likelihood ratios (−LR) (S = 96.72%, Sp = 89.47%, +LR = 9.1 and −LR = 0.03) than ACE-Pe (S = 96.72%, Sp = 63.16%, +LR = 2.62 and −LR = 0.05) and MMSE-Pe (S = 90.16%, Sp = 78.95%, +LR = 4.28 and −LR = 0.12). In the multiple regression analysis, the IFS-Pe was not affected by age, sex or years of schooling. Conclusion: The IFS-Pe has the best diagnostic accuracy for detecting VCI and discriminating between pre-dementia (VCI-ND) and dementia (VD) stages.
UR - http://www.scopus.com/inward/record.url?scp=85102930372&partnerID=8YFLogxK
U2 - 10.1002/gps.5531
DO - 10.1002/gps.5531
M3 - Artículo
C2 - 33682923
AN - SCOPUS:85102930372
SN - 0885-6230
VL - 37
JO - International Journal of Geriatric Psychiatry
JF - International Journal of Geriatric Psychiatry
IS - 1
M1 - GPS5531
ER -