Phenotypic detection of antimicrobial resistance mechanisms of Escherichia coli isolates from enteric infections in pigs from technified farms

C. Michelle Monterroso, Guillermo Salvatierra R., S. André Sedano, E. Sonia Calle

Resultados de investigaciones: Contribución a una revistaArtículo


The aim of this study was to detect the antimicrobial resistance mechanisms of 36 Escherichia coli isolates to beta-lactams, quinolones and aminoglycosides using the Kirby-Bauer technique. Thirty-six E. coli isolates from pigs of technified production farms obtained during the 2010-2015 period were used. Fifteen antimicrobials of importance in human and veterinary medicine were tested. The isolates showed resistance mainly to nalidixic acid (89%, 32/36), cloxacillin (83%, 30/36) and amoxicillin-clavulanic acid (69%, 25/36). Only 3% (1/36) were AmpC producers, 42% (15/36) showed a possible mutation in gyrA and 14% (5/36) at least two possible mutations in gyrA or gyrA+parC. In addition, 33% (12/36) showed high probabilities of presence of qnr genes. The enzymes associated to aminoglycoside resistance mechanism were positive in 39% (14/36) to AAC (6’), 28% (10/36) to ANT (2") and 11% (4/36) to AAC (3) IV.
Idioma originalEspañol
Páginas (de - a)455-464
Número de páginas10
RevistaRevista de Investigaciones Veterinarias del Peru
Estado de la publicaciónPublicada - 1 ene 2019

    Huella digital

Palabras clave

  • Antimicrobial resistance
  • Escherichia coli
  • Pigs
  • Public health
  • Resistance mechanisms

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