Case report: Recurrent hypokalemic periodic paralysis associated with distal renal tubular acidosis (type 1) and hypothyroidism secondary to hashimoto´s thyroiditis [version 2; referees: 2 approved]

E. Dante Meregildo-Rodríguez, Virgilio E. Failoc-Rojas

Resultado de la investigación: Contribución a una revistaArtículoInvestigaciónrevisión exhaustiva

Resumen

© 2019 Meregildo-Rodríguez ED and Failoc-Rojas VE. Background: Hypokalemic periodic paralysis (HypoKPP) is characterized by transient episodes of flaccid muscle weakness. We describe the case of a teenaged boy with HypoKPP and hyperthyroidism due to Hashimoto's thyroiditis with initial manifestation of renal tubular acidosis. This combination is rare and little described previously in men. Case presentation: A 17-year-old boy was admitted after three days of muscular weakness and paresthesia in the lower limbs with an ascending evolution, leading to prostration. Decreased strength was found in the lower limbs without a defined sensory level, reduced patellar and ankle reflexes. Positive antithyroid antibodies were found. He received hydration treatment, IV potassium and levothyroxine, with which there was a clinical improvement. Other examinations led to the diagnosis of type 1 renal tubular acidosis. Conclusion: HypoKPP is a rare disorder characterized by acute episodes of muscle weakness. Type 1 renal tubular acidosis can occur as a consequence of thyroiditis, which is explained by the loss of potassium. This combination is unusually rare, and has not been described before in men. The etiopathogenesis of the disease as well as a dynamic explanation of what happened with the patient are discussed in this report.
Idioma originalInglés estadounidense
PublicaciónF1000Research
DOI
EstadoPublicada - 1 ene 2019

Huella dactilar

Hypokalemic Periodic Paralysis
Renal Tubular Acidosis
Hashimoto Disease
Hypothyroidism
Muscle
Muscle Weakness
Potassium
Thyroxine
Hydration
Lower Extremity
A 17
Thyroiditis
Antibodies
Paresthesia
Hyperthyroidism
Ankle
Reflex

Citar esto

@article{8e530a028de349a68cf34b1bb8ca4ecf,
title = "Case report: Recurrent hypokalemic periodic paralysis associated with distal renal tubular acidosis (type 1) and hypothyroidism secondary to hashimoto´s thyroiditis [version 2; referees: 2 approved]",
abstract = "{\circledC} 2019 Meregildo-Rodr{\'i}guez ED and Failoc-Rojas VE. Background: Hypokalemic periodic paralysis (HypoKPP) is characterized by transient episodes of flaccid muscle weakness. We describe the case of a teenaged boy with HypoKPP and hyperthyroidism due to Hashimoto's thyroiditis with initial manifestation of renal tubular acidosis. This combination is rare and little described previously in men. Case presentation: A 17-year-old boy was admitted after three days of muscular weakness and paresthesia in the lower limbs with an ascending evolution, leading to prostration. Decreased strength was found in the lower limbs without a defined sensory level, reduced patellar and ankle reflexes. Positive antithyroid antibodies were found. He received hydration treatment, IV potassium and levothyroxine, with which there was a clinical improvement. Other examinations led to the diagnosis of type 1 renal tubular acidosis. Conclusion: HypoKPP is a rare disorder characterized by acute episodes of muscle weakness. Type 1 renal tubular acidosis can occur as a consequence of thyroiditis, which is explained by the loss of potassium. This combination is unusually rare, and has not been described before in men. The etiopathogenesis of the disease as well as a dynamic explanation of what happened with the patient are discussed in this report.",
author = "Meregildo-Rodr{\'i}guez, {E. Dante} and Failoc-Rojas, {Virgilio E.}",
year = "2019",
month = "1",
day = "1",
doi = "10.12688/f1000research.15662.2",
language = "American English",
journal = "F1000Research",
issn = "2046-1402",
publisher = "F1000Research",

}

Case report: Recurrent hypokalemic periodic paralysis associated with distal renal tubular acidosis (type 1) and hypothyroidism secondary to hashimoto´s thyroiditis [version 2; referees: 2 approved]. / Meregildo-Rodríguez, E. Dante; Failoc-Rojas, Virgilio E.

En: F1000Research, 01.01.2019.

Resultado de la investigación: Contribución a una revistaArtículoInvestigaciónrevisión exhaustiva

TY - JOUR

T1 - Case report: Recurrent hypokalemic periodic paralysis associated with distal renal tubular acidosis (type 1) and hypothyroidism secondary to hashimoto´s thyroiditis [version 2; referees: 2 approved]

AU - Meregildo-Rodríguez, E. Dante

AU - Failoc-Rojas, Virgilio E.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - © 2019 Meregildo-Rodríguez ED and Failoc-Rojas VE. Background: Hypokalemic periodic paralysis (HypoKPP) is characterized by transient episodes of flaccid muscle weakness. We describe the case of a teenaged boy with HypoKPP and hyperthyroidism due to Hashimoto's thyroiditis with initial manifestation of renal tubular acidosis. This combination is rare and little described previously in men. Case presentation: A 17-year-old boy was admitted after three days of muscular weakness and paresthesia in the lower limbs with an ascending evolution, leading to prostration. Decreased strength was found in the lower limbs without a defined sensory level, reduced patellar and ankle reflexes. Positive antithyroid antibodies were found. He received hydration treatment, IV potassium and levothyroxine, with which there was a clinical improvement. Other examinations led to the diagnosis of type 1 renal tubular acidosis. Conclusion: HypoKPP is a rare disorder characterized by acute episodes of muscle weakness. Type 1 renal tubular acidosis can occur as a consequence of thyroiditis, which is explained by the loss of potassium. This combination is unusually rare, and has not been described before in men. The etiopathogenesis of the disease as well as a dynamic explanation of what happened with the patient are discussed in this report.

AB - © 2019 Meregildo-Rodríguez ED and Failoc-Rojas VE. Background: Hypokalemic periodic paralysis (HypoKPP) is characterized by transient episodes of flaccid muscle weakness. We describe the case of a teenaged boy with HypoKPP and hyperthyroidism due to Hashimoto's thyroiditis with initial manifestation of renal tubular acidosis. This combination is rare and little described previously in men. Case presentation: A 17-year-old boy was admitted after three days of muscular weakness and paresthesia in the lower limbs with an ascending evolution, leading to prostration. Decreased strength was found in the lower limbs without a defined sensory level, reduced patellar and ankle reflexes. Positive antithyroid antibodies were found. He received hydration treatment, IV potassium and levothyroxine, with which there was a clinical improvement. Other examinations led to the diagnosis of type 1 renal tubular acidosis. Conclusion: HypoKPP is a rare disorder characterized by acute episodes of muscle weakness. Type 1 renal tubular acidosis can occur as a consequence of thyroiditis, which is explained by the loss of potassium. This combination is unusually rare, and has not been described before in men. The etiopathogenesis of the disease as well as a dynamic explanation of what happened with the patient are discussed in this report.

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85060034080&origin=inward

UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85060034080&origin=inward

U2 - 10.12688/f1000research.15662.2

DO - 10.12688/f1000research.15662.2

M3 - Article

JO - F1000Research

JF - F1000Research

SN - 2046-1402

ER -