Cardiotoxicidad asociado al uso de carmustina: Reporte de caso en farmacovigilancia

L. Yesenia Rodríguez-Tanta, Tania del Pilar Solis-Yucra, Alfredo Gabriel Wong-Chang, Virgilio E. Failoc-Rojas

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

Resumen

Background: Carmustine is an alkylating agent used in the treatment of myeloma, lymphomas and other cancers. Cardiotoxicity due to carmustine is a rare adverse reaction that must be identified early to prevent fatal outcomes. Report case: We present an unusual case of acute cardiac toxicity related to the intravenous administration of carmustine. After stopping the carmustine, patient received symptomatic treatment and, finally was fully recovered. The case was reported as adverse drug reaction and we performed a pharmacovigilance causality assessment between carmustine and cardiotoxicity, resulting in probable (final score = 7). Conclusions: This case might be considered as a signal in pharmacovigilance. Clinicians should be aware of the potential risk of cardiotoxicity in patients exposed to carmustine. It is recommended to implement active pharmacovigilance to chemotherapy.

Título traducido de la contribuciónCarmustine-induced cardiotoxicity: A pharmacovigilance case report
Idioma originalEspañol
Páginas (desde-hasta)595-598
Número de páginas4
PublicaciónRevista del Cuerpo Medico Hospital Nacional Almanzor Aguinaga Asenjo
Volumen14
N.º4
DOI
EstadoPublicada - oct. 2021

Palabras clave

  • cardiotoxicity
  • carmustine
  • non-Hodgkin lymphoma
  • pharmacovigilance. (Source: DeCS-BIREME)

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