Association between anxiety and severe quality-of-life impairment in postmenopausal women: Analysis of a multicenter Latin American cross-sectional study

Jorge L. Núñez-Pizarro, Alejandro González-Luna, Edward Mezones Holguin, Juan E. Blümel, Germán Barón, Ascanio Bencosme, Zully Benítez, Luz M. Bravo, Andrés Calle, Daniel Flores, María T. Espinoza, Gustavo Gómez, José A. Hernández-Bueno, Mabel Martino, Selva Lima, Alvaro Monterrosa, Desiree Mostajo, Eliana Ojeda, William Onatra, Hugo SánchezKonstantinos Tserotas, María S. Vallejo, Silvina Witis, María C. Zúñiga, Peter Chedraui

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

14 Citas (Scopus)

Resumen

Objective: To evaluate associations between anxiety and severe impairment of quality of life (QoL) in Latin American postmenopausal women. Methods: This was a secondary analysis of a multicenter cross-sectional study among postmenopausal women aged 40 to 59 from 11 Latin American countries. We evaluated anxiety (The Goldberg Depression and Anxiety Scale), and QoL (Menopause Rating Scale [MRS]), and included sociodemographic, clinical, lifestyle, and anthropometric variables in the analysis. Poisson family generalized linear models with robust standard errors were used to estimate prevalence ratios (PRs) and 95% CIs. There were two adjusted models: a statistical model that included variables associated with the outcomes in bivariate analyses, and an epidemiologic model that included potentially confounding variables from literature review. Results: Data from 3,503 women were included; 61.9% had anxiety (Goldberg). Severe QoL impairment (total MRS score ≥17) was present in 13.7% of women, as well as severe symptoms (MRS subscales): urogenital (25.5%), psychological (18.5%), and somatic (4.5%). Anxiety was independently associated with severe QoL impairment and severe symptoms in the epidemiological (MRS total score: PR 3.6, 95% CI, 2.6-5.0; somatic: 5.1, 95% CI, 2.6-10.1; psychological: 2.8, 95% CI, 2.2-3.6; and urogenital: 1.4, 95% CI, 1.2-1.6) and the statistical model (MRS total score: PR 3.5, 95% CI, 2.6-4.9; somatic: 5.0, 95% CI, 2.5-9.9; psychological: 2.9, 95% CI, 2.2-3.7; and urogenital: 1.4; 95% CI, 1.2-1.6). Conclusions: In this postmenopausal Latin American sample, anxiety was independently associated with severe QoL impairment. Hence, screening for anxiety in this population is important.

Idioma originalInglés
Páginas (desde-hasta)645-652
Número de páginas8
PublicaciónMenopause
Volumen24
N.º6
DOI
EstadoPublicada - 1 jun 2017
Publicado de forma externa

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