Aplasia medular asociado con virus linfotrópico humano de células T tipo 1 (HTLV-1): Reporte de un caso

Maycol Suker Ccorahua-Rios, Estefani Chanco-Tupa, Ana Claudia Santander-Cahuantico, Noé Atamari-Anahui

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

Resumen

Background: Medullary aplasia is a disease characterized by pancytopenia with hypocellular bone marrow. Most of these are acquired and can be idiopathic or secondary to bone marrow damage produced by physical, chemical or infectious agents. HTLV-1 is an intracellular retrovirus that is transmitted by prolonged breastfeeding, sexual intercourse, and blood transfusions. Case description: We report the case of a 28-year-old woman who presented petechiae, gingivorrhagia, and generalized paleness. In the laboratory examination, severe pancytopenia was found, HTLV-1 positive, and in the bone marrow aspirate, marked hypocellularity. She received antibiotics, antifungals, antivirals, and immunosuppressive agents with a steady course. Conclusions: HTLV-1 infection is common in Peru; however, its association with medullary aplasia is poorly described. Hematopoietic stem-cell transplantation is an alternative treatment in case of failure to respond to immunosuppressive therapy.

Título traducido de la contribuciónMedullary aplasia associated with Human T-Cell Lymphotropic Virus Type 1 (HTLV-1): A Case Report
Idioma originalEspañol
Páginas (desde-hasta)207-210
Número de páginas4
PublicaciónRevista del Cuerpo Medico Hospital Nacional Almanzor Aguinaga Asenjo
Volumen14
N.º2
DOI
EstadoPublicada - 30 jun 2021

Palabras clave

  • Hematopoietic Stem Cell Transplantation
  • HTLV-1
  • Pancytopenia
  • Peru
  • Retrovirus

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