Alteraciones hematológicas en trabajadores expuestos ocupacionalmente a mezcla de benceno-tolueno-xileno (BTX) en una fábrica de pinturas

Luis Haro-García, Nadia Vélez-Zamora, Guadalupe Aguilar-Madrid, Susana Guerrero-Rivera, Vanessa Sánchez-Escalante, Sergio R. Muñoz, Edward Mezones-Holguín, Cuauhtémoc Juárez-Pérez

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

6 Citas (Scopus)

Resumen

Objectives. Evaluate the three blood cell series and identify the presence of hypochromia, macrocytosis, leucopenia, lymphopenia, and thrombocytopenia in a group of workers exposed to the mixture of benzene-toluene-xylene (BTX). Materials and methods. A cross-sectional study which included 97 workers from a paint factory in Mexico. The participants underwent conventional blood count and tests for potential cumulative daily dose of BTX fumes, to estimate exposure. Results. From the total of workers, 19.6% showed macrocytosis, 18.6%, lymphopenia, hypochromia 10.3%, 7.2% and 5.2% thrombocytopenia leukopenia. The crude association of macrocytosis with exposure to high doses of BTX mixture was the only with statistical significance (OR: 3.6, 95% CI 1.08 to 13.9, P = 0.02), and the base for a logistic regression model (OR: 6.7, 95% CI 1.33 to 13.55, P = 0.02) adjusted for age, alcohol consumption, and smoking. Conclusions. All blood cytological components analyzed demonstrated mild changes, potentially associated with exposure to the mixture of BTX. Macrocytosis could constitute an early manifestation worthy for surveillance.

Título traducido de la contribuciónBlood disorders among workers exposed to a mixture of benzene-toluene-xylene (BTX) in a paint factory
Idioma originalEspañol
Páginas (desde-hasta)181-187
Número de páginas7
PublicaciónRevista Peruana de Medicina Experimental y Salud Publica
Volumen29
N.º2
DOI
EstadoPublicada - 2012
Publicado de forma externa

Palabras clave

  • Benzene derivatives
  • Hematologic diseases
  • Occupational health
  • Workers

Huella

Profundice en los temas de investigación de 'Alteraciones hematológicas en trabajadores expuestos ocupacionalmente a mezcla de benceno-tolueno-xileno (BTX) en una fábrica de pinturas'. En conjunto forman una huella única.

Citar esto