TY - JOUR
T1 - Adherence to antiretroviral therapy among HIV patients at a hospital in Tacna, Peru
AU - Miranda-Chavez, Brayan
AU - Mejia-Copaja, Monica
AU - Taype-Rondan, Alvaro
N1 - Publisher Copyright:
© 2024 The Authors
PY - 2024/11/1
Y1 - 2024/11/1
N2 - Objective: This study aims to provide an overview of antiretroviral therapy adherence and its related factors within a hospital in southern Peru. Materials and methods: We conducted an analytical cross-sectional study spanning from April to October 2022. This study involved a review of medical records and the administration of a survey to individuals living with Human Immunodeficiency Virus. Adherence to antiretroviral treatment was assessed using the CEAT-HIV (Questionnaire for the Evaluation of Antiretroviral Treatment Adherence), and was categorized as high, adequate, insufficient, or low. The statistical analysis included the calculation of crude and adjusted prevalence ratios (PRs). Results: Our study comprised 300 participants, with a median age of 30 years, predominantly male (78.3 %). Among these individuals, 83 % exhibited low or insufficient adherence to antiretroviral treatment according to the CEAT-VIH scale. Notably, patients with a viral load >50,000 copies/ml scored higher on the CEAT-VIH scale than those with a viral load <400 (adjusted PR: 2.78, 95 % CI: 1.21 to 6.40). Furthermore, a higher level of education and a viral load below 400 copies/ml were associated to higher scores in the treatment compliance dimension of the CEAT-VIH scale. Conclusion: Eight out of ten evaluated patients exhibited low or insufficient adherence. While lower adherence was correlated with lower education, the connection between viral load and adherence remains inconclusive.
AB - Objective: This study aims to provide an overview of antiretroviral therapy adherence and its related factors within a hospital in southern Peru. Materials and methods: We conducted an analytical cross-sectional study spanning from April to October 2022. This study involved a review of medical records and the administration of a survey to individuals living with Human Immunodeficiency Virus. Adherence to antiretroviral treatment was assessed using the CEAT-HIV (Questionnaire for the Evaluation of Antiretroviral Treatment Adherence), and was categorized as high, adequate, insufficient, or low. The statistical analysis included the calculation of crude and adjusted prevalence ratios (PRs). Results: Our study comprised 300 participants, with a median age of 30 years, predominantly male (78.3 %). Among these individuals, 83 % exhibited low or insufficient adherence to antiretroviral treatment according to the CEAT-VIH scale. Notably, patients with a viral load >50,000 copies/ml scored higher on the CEAT-VIH scale than those with a viral load <400 (adjusted PR: 2.78, 95 % CI: 1.21 to 6.40). Furthermore, a higher level of education and a viral load below 400 copies/ml were associated to higher scores in the treatment compliance dimension of the CEAT-VIH scale. Conclusion: Eight out of ten evaluated patients exhibited low or insufficient adherence. While lower adherence was correlated with lower education, the connection between viral load and adherence remains inconclusive.
KW - Adherence
KW - CD4 lymphocyte count
KW - HIV seroprevalence
KW - Viral load
UR - http://www.scopus.com/inward/record.url?scp=85206086288&partnerID=8YFLogxK
U2 - 10.1016/j.cegh.2024.101803
DO - 10.1016/j.cegh.2024.101803
M3 - Artículo
AN - SCOPUS:85206086288
SN - 2213-3984
VL - 30
JO - Clinical Epidemiology and Global Health
JF - Clinical Epidemiology and Global Health
M1 - 101803
ER -