Acute disseminated encephalomyelitis and COVID-19: A systematic synthesis of worldwide cases

Laura Zelada-Ríos, Kevin Pacheco-Barrios, Milagros Galecio-Castillo, Cesar Yamunaqué-Chunga, Kelvin Álvarez-Toledo, Ricardo Otiniano-Sifuentes

Resultado de la investigación: Contribución a una revistaArtículo de revisiónrevisión exhaustiva

Resumen

Acute disseminated encephalomyelitis (ADEM) has been reported after coronavirus disease 2019 (COVID-19). In this review, we systematically included worldwide reported cases on this association. We included 30 case reports (pediatric and adults) and explored epidemiological and clinical evidence. We described time to diagnosis, clinical, imaging, and laboratory features, response to treatment regimens, and differences regarding severity. Also, an original case report was presented. Neurologists must be alert to the occurrence of multifocal neurological symptoms with or without encephalopathy in patients recovered from COVID-19. Timely MRI studies should be performed to establish the diagnosis and to consider early corticosteroid-based treatment.

Idioma originalInglés
Número de artículo577674
PublicaciónJournal of Neuroimmunology
Volumen359
DOI
EstadoPublicada - 15 oct 2021
Publicado de forma externa

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