Validation of the RUDAS for the Identification of Dementia in Illiterate and Low-Educated Older Adults in Lima, Peru

Nilton Custodio, Rosa Montesinos, David Lira, Eder Herrera-Perez, Kristhy Chavez, Willyams Reynoso-Guzman, Maritza Pintado-Caipa, José Cuenca, Carlos Gamboa, Tatiana Metcalf

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12 Scopus citations

Abstract

Objectives: To evaluate the performance of the Peruvian version of the Rowland Universal Dementia Assessment Scale (RUDAS-PE) in discriminating between controls and patients with mild cognitive impairment (MCI) and dementia in an illiterate population with low-levels of education. Methods: We compared the cognitive performance of 187 elderly subjects who were illiterate (controls n = 60; MCI n = 64; dementia n = 63). Neuropsychological measures included the RUDAS-PE, Mini-Mental State Examination (MMSE), INECO Frontal Screening (IFS), and Pfeffer Functional Activities Questionnaire (PFAQ). The results were compared to a neuropsychological evaluation (gold standard), including use of Clinical Dementia Rating (CDR) scores. Results: We found a Cronbach's alpha was 0.65; Spearman's correlation coefficient was 0.79 (p < 0.01). The area under the receiver operating characteristics curve for the RUDAS to discriminate dementia from MCI was 98.0% with an optimal cut-off <19 (sensitivity 95%, specificity 97%); whereas, to differentiate MCI and controls was 98.0% with an optimal cut-off <23 (sensitivity 89%, specificity 93%). Conclusions: Based on its excellent psychometric properties, we find the RUDAS-PE suitable to aid in the opportune detection of dementia in a geriatric illiterate population with low-levels of education.

Original languageEnglish
Article number374
JournalFrontiers in Neurology
Volume11
DOIs
StatePublished - 5 May 2020

Keywords

  • Alzheimer's disease
  • brief cognitive assessment
  • dementia
  • illiteracy
  • mild cognitive impairment
  • neurocognitive disorders
  • neuropsychology

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