TY - JOUR
T1 - [Severe decompensation of hepatitis e in a patient with autoimmune hepatitis: a case report].
AU - Valenzuela, V.
AU - Pinto, J.
AU - Padilla, M.
AU - Piscoya, A.
AU - De Los Rios, R.
AU - Surco, Y.
AU - Bravo, E.
AU - Huerta-Mercado, J.
PY - 2012/1/1
Y1 - 2012/1/1
N2 - We report the case of a patient who initially made the diagnosis of acute hepatitis E virus with a clinical picture of jaundice with elevated liver enzymes and HEV IgM (+), but chronic evolution (More than 6 months) without being an immunosuppressed patient, forced us to exclude different causes that may produce chronic liver disease. And hypergammaglobulinemia was detected in liver biopsy: interface hepatitis, mixed inflammatory infiltrate with predominance of lymphocytes, and presence of portal-portal fibrous tracts, suggestive of severe active chronic hepatitis may be secondary to autoimmune hepatitis associated with hepatitis virus infection E. With these findings, we decided to start treatment for autoimmune hepatitis with prednisone and azathioprine, leading to a decrease in transaminases and coagulation profile to normal, which helped confirm the diagnosis of autoimmune hepatitis and decompensated manifested by acute virus infection of hepatitis E. Full report the case and a review of the literature.
AB - We report the case of a patient who initially made the diagnosis of acute hepatitis E virus with a clinical picture of jaundice with elevated liver enzymes and HEV IgM (+), but chronic evolution (More than 6 months) without being an immunosuppressed patient, forced us to exclude different causes that may produce chronic liver disease. And hypergammaglobulinemia was detected in liver biopsy: interface hepatitis, mixed inflammatory infiltrate with predominance of lymphocytes, and presence of portal-portal fibrous tracts, suggestive of severe active chronic hepatitis may be secondary to autoimmune hepatitis associated with hepatitis virus infection E. With these findings, we decided to start treatment for autoimmune hepatitis with prednisone and azathioprine, leading to a decrease in transaminases and coagulation profile to normal, which helped confirm the diagnosis of autoimmune hepatitis and decompensated manifested by acute virus infection of hepatitis E. Full report the case and a review of the literature.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84875023999&origin=inward
UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84875023999&origin=inward
M3 - Scientific review
SN - 1609-722X
SP - 187
EP - 191
JO - Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú
JF - Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú
ER -
