Perfil Clínico y Demográfico de Pacientes con Enfermedad de Parkinson: Experiencia en un Centro de Referencia de Perú

Objective: To describe the demographic and clinical characteristics of patients with Parkinson's disease treated at a national reference hospital in Peru. Methods: We conducted a retrospective cross-sectional study that included 35 adult patients (18 years and older) with Parkinson's disease treated at the Neurology outpatient service of the Edgardo Rebagliati Martins National Hospital during 2020. We recorded the clinical and demographic information of the medical records. clinics. We performed bivariate analysis to compare the covariates of in-terest with the presence of complications and the Hoehn and Yahr stage. Results: The average time of illness was more than 5 years from diagnosis and most presented motor complications, the treatment they received was almost entirely levodopa and 37% received treatment with deep brain stimulation. In the bivariate analysis according to the Hoehn and Yahr stages with the variants age, clinical variant, time of illness and being subjected to Deep Brain Stimulation, no significant differences were found. In the bivariate analysis according to the presence of complications, statistical differences were found between complications and tertiles of age (p=0.008) and the median time of illness (p=0.010). Conclusion: We report a prolonged disease time in the included patients, most of them presented motor complications, their main treatment was levodopa and a high percentage of deep brain stimulation. It is important to propose multicenter studies in reference centers for Parkinson's management that allow us to have a better overview of the clinical and demographic situation of these patients in our population.