Mortality and associated factors in chronic kidney disease patients under hemodialysis in a Peruvian hospital

Jhon Loaiza-Huallpa, Mirian Condori-Huaraka, Gabriel H. Quispe-Rodríguez, María Pilar Pinares-Valderrama, Ana Isabel Cruz-Huanca, Noé Atamari-Anahui, Percy Herrera-Añazco, Rufo Mercado-Phuño, Rubén Nieto-Portocarrero, Christian R. Mejia

Research output: Contribution to journalArticle

Abstract

Introduction: Chronic kidney disease is a health problem in Perú. Objective: To determine the mortality and the associated factors in chronic kidney disease patients under hemodialysis in an incident population in a Peruvian hospital. Material and Methods: A retrospective cohort study was conducted in patients admitted to the chronic hemodialysis program at Hospital Antonio Lorena (Cusco-Peru), from 2010 to 2016. Kaplan-Meier method was used for the survival analysis to determine the factors associated with mortality, Cox´s Regression was carried out, obtaining Hazard Ratio (HR) and 95% confidence intervals (95% CI). Results: A total of 187 patients were studied, with a mean age of 57 years (interquartile range: 43-66). The 47% (89) of patients died during follow-up. Mortality rate was 24 deaths / 100 people-per year (95% CI: 19.6-29.6). The mean survival rate was 2.8 years (95% CI: 1.9-4.0). Dilatation of the left atrium in the echocardiography (HR: 2.63; 95% CI: 1.03-6.69; p=0.041), a white blood cell count ≥ 12x103u/mm3 (HR: 6.86; 95% CI: 2.08-22.66; p=0.002), and hemoglobin <7 g/dL (HR: 3.62; 95% CI: 1.05-12.48; p=0.041) were associated with mortality. Conclusions: A low frequency of survival was found, which was associated with potentially modifiable factors.

Translated title of the contributionMortality and associated factors in chronic kidney disease patients under hemodialysis in a Peruvian hospital
Original languageSpanish
Pages (from-to)164-175
Number of pages12
JournalRevista Habanera de Ciencias Medicas
Volume18
Issue number1
StatePublished - 1 Jan 2019

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    Loaiza-Huallpa, J., Condori-Huaraka, M., Quispe-Rodríguez, G. H., Pinares-Valderrama, M. P., Cruz-Huanca, A. I., Atamari-Anahui, N., Herrera-Añazco, P., Mercado-Phuño, R., Nieto-Portocarrero, R., & Mejia, C. R. (2019). Mortalidad y factores asociados en pacientes con enfermedad renal crónica en hemodiálisis en un hospital peruano. Revista Habanera de Ciencias Medicas, 18(1), 164-175. http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1729-519X2019000100164