Meta-analysis of predictors of healthcare-associated Clostridioides difficile infection

Jesse Fajnzylber, William M. Patterson, Neil Nero, Adrian V. Hernandez, Abhishek Deshpande*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Our systematic review and meta-analysis of 40 studies (n = 3,905,559) identified gastric acid suppressants, recent hospitalization, antibiotic exposure, and certain comorbidities as independent predictors of healthcare-associated Clostridioides difficile infection (HA-CDI) among adult inpatients. Targeted antibiotic stewardship and judicious use of gastric acid suppressants can reduce the incidence of HA-CDI.

Original languageEnglish
Article numbere202
JournalAntimicrobial Stewardship and Healthcare Epidemiology
Volume4
Issue number1
DOIs
StatePublished - 14 Nov 2024

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