Flavonoides totales, metales bioactivadores y actividad antioxidante in vitro del extracto etanólico de Solanum radicans L.f.

Translated title of the contribution: Total flavonoids, bioactivating metals and antioxidant activity in vitro of ethanolic extract of Solanum radicans L.f.

Jorge García-Ceccarelli, Felipe Surco-Laos, María Bendezú-Acevedo, Juan Palomino-Jhong, Doris Laos-Anchante, Haydee Chávez-Orellana, Eddie Loyola-Gonzales, Eliades Yarasca-Carlos, Ana María Muñoz, Angel T. Alvarado*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Introduction: Solanum radicans L.f. (huallpachaqui) is a plant species with potential bioactive compounds that have antioxidant properties, widely used in traditional medicine in Peru. Scientific studies supporting its medicinal use are scarce. Objective: To determine the presence of total flavonoids, bioactivating metals and in vitro antioxidant activity of ethanolic extract of Solanum radicans L.f. Methods: The powdered material from the aerial part of S. radicans L.f. was extracted with 96° ethanol by maceration. The total phenolic content was determined by the Folin-Ciocalteu method, total content of flavonoids, and metals by flame atomic absorption spectrophotometry (FAAS); antioxidant activity by three in vitro methods. Results: In the study that was carried out, total phenolic content (CPT: 39.07±0.63 mg GAE/g), total flavonoid content (CFT: 65.89 ± 0.22 mg QAE/g) were estimated; metals in mg/100 g (Calcium 9.4±0.02; Copper 0.7±0.01; Magnesium 15.8 ± 0.15; Zinc 1.4 ± 0.02); antioxidant activity: DPPH IC50 7,20±0,14; ABTS 2.31±0.01 TEAC mg/g; FRAP 1.55±0.01 TEAC mg/g; Pearson coefficient DPPH/CPT (0.7804), FRAP/CFT (0.5080); significantly different p < 0.05. Conclusions: The ethanolic extract of the aerial parts of S. radicans L.f. contains phenolic compounds and flavonoids, with antioxidant activity in three in vitro methods.

Translated title of the contributionTotal flavonoids, bioactivating metals and antioxidant activity in vitro of ethanolic extract of Solanum radicans L.f.
Original languageSpanish
Article numbere802
JournalRevista Cubana de Farmacia
Volume55
Issue number4
StatePublished - 1 Oct 2022

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