TY - JOUR
T1 - Enfermedad de Kawasaki, enfermedad similar a Kawasaki y MIS-C asociado a COVID-19 en niños
T2 - revisión sistemática
AU - Barboza, Joshuan J.
AU - Chambergo-Michilot, Diego
AU - Velasquez-Sotomayor, Mariana
AU - Silva-Rengifo, Christian
AU - Alarcon-Ruiz, Christoper A.
AU - Rodriguez-Morales, Alfonso J.
AU - Malaga, German
AU - Pérez-Gaxiola, Giordano
N1 - Publisher Copyright:
© 2022 Asociacion Colombiana de Infectologia. All rights reserved.
PY - 2022
Y1 - 2022
N2 - Objective: To synthesize the epidemiological and clinical characteristics of COVID-19 children with MIS-C, KLD and EK.Methods: Databases and preprints were searched until May 31, 2021. Reports/case series that evaluated the clinical features of EK, KLD, or MIS-C in pediatric patients with COVID-19 were included. Results: Sixteen studies were included (six case reports and ten case series, 367 patients total, 58 patients with EK, 87 with KLD, and 290 patients with MIS-C); with ages ranging from 6 months to 10 years, and 62% were female. Positive COVID-19 was observed in 75.2%. Regarding EK, KLD and MIS-C, the reported clinical characteristics were compatible with the standardized diagnostic pictures in the context of COVID-19. The duration of hospitalization was 5 to 14 days for EK and 4.3 to 13 for MIS-C. Eleven patients with MIS-C (2.8%) needed ECMO. Eleven patients with MIS-C (2.8%) needed ECMO. Six patients with MIS-C were reported dead. Eight studies reported patients in the ICU. Conclusions: Children with COVID-19 develop EK or KLD, and can be complicated by MIS-C. Prevention, diagnosis, and treatment measures are needed.
AB - Objective: To synthesize the epidemiological and clinical characteristics of COVID-19 children with MIS-C, KLD and EK.Methods: Databases and preprints were searched until May 31, 2021. Reports/case series that evaluated the clinical features of EK, KLD, or MIS-C in pediatric patients with COVID-19 were included. Results: Sixteen studies were included (six case reports and ten case series, 367 patients total, 58 patients with EK, 87 with KLD, and 290 patients with MIS-C); with ages ranging from 6 months to 10 years, and 62% were female. Positive COVID-19 was observed in 75.2%. Regarding EK, KLD and MIS-C, the reported clinical characteristics were compatible with the standardized diagnostic pictures in the context of COVID-19. The duration of hospitalization was 5 to 14 days for EK and 4.3 to 13 for MIS-C. Eleven patients with MIS-C (2.8%) needed ECMO. Eleven patients with MIS-C (2.8%) needed ECMO. Six patients with MIS-C were reported dead. Eight studies reported patients in the ICU. Conclusions: Children with COVID-19 develop EK or KLD, and can be complicated by MIS-C. Prevention, diagnosis, and treatment measures are needed.
KW - COVID-19
KW - Kawasaki diseases
KW - Multisystemic inflammatory syndrome
UR - http://www.scopus.com/inward/record.url?scp=85129984846&partnerID=8YFLogxK
U2 - 10.22354/in.v26i2.1012
DO - 10.22354/in.v26i2.1012
M3 - Artículo de revisión
AN - SCOPUS:85129984846
SN - 0123-9392
VL - 26
SP - 137
EP - 144
JO - Infectio
JF - Infectio
IS - 2
ER -