TY - JOUR
T1 - Efficacy and Safety of Topical Application of Olive Oil for Preventing Pressure Ulcers
T2 - A Systematic Review and Meta-Analysis of Randomized Controlled Trials
AU - Hernández-Vásquez, Akram
AU - Visconti-Lopez, Fabriccio J.
AU - Cabanillas-Ramirez, Cielo
AU - Díaz-Seijas, Deysi
AU - Meléndez-Escalante, Jessica
AU - Comandé, Daniel
AU - Santero, Marilina
N1 - Publisher Copyright:
© 2022 by the authors.
PY - 2022/11
Y1 - 2022/11
N2 - The purpose was to identify and summarize the existing evidence on the efficacy and safety of the topical application of olive oil for preventing pressure ulcers (PUs). We included only randomized controlled trials (RCTs) involving patients at risk of developing PUs, testing the topical application of olive oil versus other products for PU prevention. We assessed the risk of bias using the RoB 2 tool, and the certainty of the evidence with GRADE. Four RCTs met the eligibility criteria. All studies were judged at a low risk of bias overall. The meta-analysis showed that the clinical efficacy of olive oil for prevention occurs by reducing the incidence of PUs (RR = 0.56, 95% CI = 0.30 to 0.79, I2 = 0%); with no differences in adverse effects, it may be associated with a shorter development time of PUs and shorter hospital stays. The certainty of the evidence assessed by the GRADE approach was moderate and low. The topical application of olive oil is effective and safe in reducing the incidence of PUs compared to other treatments. These findings could provide new insights into olive oil as a preventive and alternative treatment for PUs as it is accessible and inexpensive compared to other products.
AB - The purpose was to identify and summarize the existing evidence on the efficacy and safety of the topical application of olive oil for preventing pressure ulcers (PUs). We included only randomized controlled trials (RCTs) involving patients at risk of developing PUs, testing the topical application of olive oil versus other products for PU prevention. We assessed the risk of bias using the RoB 2 tool, and the certainty of the evidence with GRADE. Four RCTs met the eligibility criteria. All studies were judged at a low risk of bias overall. The meta-analysis showed that the clinical efficacy of olive oil for prevention occurs by reducing the incidence of PUs (RR = 0.56, 95% CI = 0.30 to 0.79, I2 = 0%); with no differences in adverse effects, it may be associated with a shorter development time of PUs and shorter hospital stays. The certainty of the evidence assessed by the GRADE approach was moderate and low. The topical application of olive oil is effective and safe in reducing the incidence of PUs compared to other treatments. These findings could provide new insights into olive oil as a preventive and alternative treatment for PUs as it is accessible and inexpensive compared to other products.
KW - bedsore
KW - GRADE approach
KW - humans
KW - olive oil
KW - pressure ulcer
KW - prevention and control
KW - randomized controlled trial
KW - Pressure Ulcer/prevention & control
KW - Humans
KW - Olive Oil
KW - Randomized Controlled Trials as Topic
KW - Incidence
KW - Suppuration
UR - http://www.scopus.com/inward/record.url?scp=85142542984&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/d74908d9-3d17-3046-82a0-fa858540f1e0/
U2 - 10.3390/ijerph192214921
DO - 10.3390/ijerph192214921
M3 - Artículo
C2 - 36429639
AN - SCOPUS:85142542984
SN - 1661-7827
VL - 19
JO - International Journal of Environmental Research and Public Health
JF - International Journal of Environmental Research and Public Health
IS - 22
M1 - 14921
ER -