Collaborative scientific production of epilepsy in Latin America from 1989 to 2018: A bibliometric analysis

Cristian Morán-Mariños*, Josmel Pacheco-Mendoza, Tatiana Metcalf, Walter De la Cruz Ramirez, Carlos Alva-Diaz

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Socioeconomic and cultural factors coupled with an inability to control many endemic and emerging diseases have resulted in a growing incidence of epilepsy cases in Latin America. This study aimed to analyze and describe scientific research output trends in epilepsy research for the period 1989-2018. Publications were extracted from Scopus indexed journals. Bibliometric analysis was used to analyze scientific output including number of annual publications, documents, and publication characteristics. A mapping analysis using VOSviewer software visualized collaborative network analysis, co-citation analysis, and keyword co-occurrence analysis. SciVal quantitatively analyzed distribution of countries, institutions, citation counts, H-index, and research collaborative partnerships. A total of 176507 records were initially retrieved after which 5636 were analyzed. Overall, an increasing trend for publication output was observed from 19 articles in 1989 to 342 in 2018; the number of publications significantly increased over the past 20 years (p = 0.0065). The majority of publications were original articles (74.4%). Brazil had the most scientific production (55.2%), followed by Mexico (15.4%) and Argentina (10%). Extra-regional collaboration was primarily with the United States, United Kingdom, and Canada; intraregional collaboration was low. The most common area of investigation by co-occurrences was "diagnostic research" (37.2%), with studies based on electroencephalography and nuclear magnetic resonance. Epilepsy research in Latin America has seen a steady growth with significant increases over the past 20 years. Brazil, Mexico, and Argentina are the most productive countries in the field collaborating primarily with extra-regional countries of high-income.

Original languageEnglish
Article numbere05493
Pages (from-to)e05493
Issue number11
StatePublished - 1 Nov 2020


  • Bibliometrics
  • Biomedical research
  • Epidemiology
  • Epilepsy
  • Information management
  • Information science
  • Intersectoral collaboration
  • Latin America
  • Network analysis
  • Neurology


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