CHARACTERISTICS OF HEMOLYTIC UREMIC SYNDROME IN PATIENTS FROM A PEDIATRIC HOSPITAL IN PERU, 2010-2020

Lisbeth Varenia Carrasco-Oros, Noé Atamari-Anahui*, Alcida Goñi-Fano, Claudia Sosa-Carmelo, Eduardo Jesús Guzmán-Quispe, Nadin Conto-Palomino, Basem Rodolfo Cabrera-Villacriz, Carla Lisette Apeña-Cabrera

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

This study aimed to describe the clinical-epidemiological, laboratory, treatment, and follow-up characteristics of patients with hemolytic uremic syndrome (HUS). The medical records of patients with HUS hospitalized at the Instituto Nacional de Salud del Niño-Breña (INSN-B) (Lima, Peru) were reviewed. We evaluated 83 patients. The median age was 22 months (interquartile range: 14 to 30 months). Of the sample, 71.1% (59) registered previous use of antibiotics. Seventy-two (86.8%) had oligoanuria and 62 (74.6%) had diarrhea. Five cultures were positive (two enterohaemorrhagic Escherichia coli). Forty-ni-ne (59%) required renal replacement therapy. No patient died during hospitalization. At one year of follow-up, seven patients developed post-HUS nephropathy. In conclusion, in INSN-B, the median age was like previous years and there was a higher frequency of oligoanuria, and renal replacement therapy compared to previous reports.

Original languageEnglish
Pages (from-to)207-212
Number of pages6
JournalRevista Peruana de Medicina Experimental y Salud Publica
Volume40
Issue number2
DOIs
StatePublished - 2023

Keywords

  • Child, Peru
  • Hemolytic uremic syndrome
  • Renal Replacement Therapy

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