TY - JOUR
T1 - CHARACTERISTICS OF HEMOLYTIC UREMIC SYNDROME IN PATIENTS FROM A PEDIATRIC HOSPITAL IN PERU, 2010-2020
AU - Carrasco-Oros, Lisbeth Varenia
AU - Atamari-Anahui, Noé
AU - Goñi-Fano, Alcida
AU - Sosa-Carmelo, Claudia
AU - Guzmán-Quispe, Eduardo Jesús
AU - Conto-Palomino, Nadin
AU - Cabrera-Villacriz, Basem Rodolfo
AU - Apeña-Cabrera, Carla Lisette
N1 - Publisher Copyright:
© 2023, Instituto Nacional de Salud. All rights reserved.
PY - 2023
Y1 - 2023
N2 - This study aimed to describe the clinical-epidemiological, laboratory, treatment, and follow-up characteristics of patients with hemolytic uremic syndrome (HUS). The medical records of patients with HUS hospitalized at the Instituto Nacional de Salud del Niño-Breña (INSN-B) (Lima, Peru) were reviewed. We evaluated 83 patients. The median age was 22 months (interquartile range: 14 to 30 months). Of the sample, 71.1% (59) registered previous use of antibiotics. Seventy-two (86.8%) had oligoanuria and 62 (74.6%) had diarrhea. Five cultures were positive (two enterohaemorrhagic Escherichia coli). Forty-ni-ne (59%) required renal replacement therapy. No patient died during hospitalization. At one year of follow-up, seven patients developed post-HUS nephropathy. In conclusion, in INSN-B, the median age was like previous years and there was a higher frequency of oligoanuria, and renal replacement therapy compared to previous reports.
AB - This study aimed to describe the clinical-epidemiological, laboratory, treatment, and follow-up characteristics of patients with hemolytic uremic syndrome (HUS). The medical records of patients with HUS hospitalized at the Instituto Nacional de Salud del Niño-Breña (INSN-B) (Lima, Peru) were reviewed. We evaluated 83 patients. The median age was 22 months (interquartile range: 14 to 30 months). Of the sample, 71.1% (59) registered previous use of antibiotics. Seventy-two (86.8%) had oligoanuria and 62 (74.6%) had diarrhea. Five cultures were positive (two enterohaemorrhagic Escherichia coli). Forty-ni-ne (59%) required renal replacement therapy. No patient died during hospitalization. At one year of follow-up, seven patients developed post-HUS nephropathy. In conclusion, in INSN-B, the median age was like previous years and there was a higher frequency of oligoanuria, and renal replacement therapy compared to previous reports.
KW - Child, Peru
KW - Hemolytic uremic syndrome
KW - Renal Replacement Therapy
UR - http://www.scopus.com/inward/record.url?scp=85172294474&partnerID=8YFLogxK
U2 - 10.17843/rpmesp.2023.402.12708
DO - 10.17843/rpmesp.2023.402.12708
M3 - Artículo
AN - SCOPUS:85172294474
SN - 1726-4634
VL - 40
SP - 207
EP - 212
JO - Revista Peruana de Medicina Experimental y Salud Publica
JF - Revista Peruana de Medicina Experimental y Salud Publica
IS - 2
ER -