Microbiological and molecular characterization of antimicrobial resistance in uropathogenic Escherichia coli from peruvian public hospitals

Pool Marcos-Carbajal, Guillermo Salvatierra, José Yareta, Jimena Pino, Nancy Vásquez, Pilar Diaz, Isabel Martínez, Percy Asmat, Carlos Peralta, Caridad Huamani, Alexander Briones, Manuel Ruiz, Nicomedes Laura, Álvaro Luque, Leonel Arapa, Pablo Tsukayama

Research output: Contribution to journalArticlepeer-review

Abstract

We characterized the antimicrobial resistance of 70 Escherichia coli isolates obtained from patients with a urinary tract infection (UTI) from 8 public hospitals in Peru. Resistance profiles were identified using the automated MicroScan® system. A standard polymerase chain reaction was used for the detection of the bla TEM, bla CTX-M, bla SHV and bla PER genes. The 65.7% (46/70) of the isolates presented a multidrug-resistant phenotype and 55.7% (39/70) were extended-spectrum beta-lactamases producers. High levels of resistance were detected for ampicillin (77,1%), ciprofloxacin (74,3%), trimethoprim/sulfamethoxazole (62,9%), cefepime (57,1%), and cefuroxime (57,1%). The bla TEM gene was the most frequent (31,4%), followed by bla CTX-M (18,6%) and bla SHV (2,9%) genes. These results show high resistance levels to antimicrobials of clinical use in E. coli isolates from hospital UTI patients in Peru.

Translated title of the contributionMicrobiological and molecular characterization of antimicrobial resistance in uropathogenic Escherichia coli from peruvian public hospitals
Original languageSpanish
Pages (from-to)119-123
Number of pages5
JournalRevista Peruana de Medicina Experimental y Salud Publica
Volume38
Issue number1
DOIs
StatePublished - 1 Jan 2021
Externally publishedYes

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