ASSOCIATION BETWEEN LOW VITAMIN B12 LEVELS AND COGNITIVE IMPAIRMENT IN ELDERLY AT THE NAVAL MEDICAL CENTER OF PERU

Andrés Cabrera-Gamonal, Carlos D. Neyra-Rivera, Jose S. Lazarte, Ericson L. Gutierrez, Fernando M. Runzer-Colmenares, José F. Parodi

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: Older adults are susceptible to malnutrition and vitamin deficiency. Objective: To determine the association between the low level of vitamin B12 and cognitive deterioration in older adults from the Naval Medical Center, located in Lima-Peru, in the period 2010-2015. Methods: An analytical cross-sectional study was carried out, based on a secondary analysis of the Texas-Cemena UTMB 2010-2015 database of the Center for Research on Aging (CIEN) of the University of San Martín de Porres. To quantify the cognitive impairment variable, the MiniMental Test was used. To analyze the association, the Chi-square test and Poisson regression were performed. Results: 57.6% of the patients were male and the mean age was 78 ± 8.4. 41.2% presented cognitive deterioration and 9.5% of the patients presented vitamin B12 deficiency. The factors independently associated with cognitive impairment were a history of cerebrovascular disease (PR= 1.38 95% CI [1.24-1.53]), depression (PR= 1.88 95% CI [1.80-1 .97]) and vitamin B12 deficiency (PR = 1.10 95% CI [1.01-1.20]). Conclusions: In the present study, an association was found between a low level of vitamin B12 and cognitive deterioration in older adults.

Translated title of the contributionASOCIACIÓN ENTRE EL BAJO NIVEL DE VITAMINA B12 Y DETERIORO COGNITIVO EN ADULTOS MAYORES DEL CENTRO MÉDICO NAVAL DEL PERÚ
Original languageEnglish
Pages (from-to)117-123
Number of pages7
JournalRevista de la Facultad de Medicina Humana
Volume23
Issue number2
DOIs
StatePublished - 2023

Keywords

  • Cognitive impairment
  • Elderly
  • Geriatrics
  • Naval Medicine
  • Peru

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