Alteraciones hematológicas en trabajadores expuestos ocupacionalmente a mezcla de benceno-tolueno-xileno (BTX) en una fábrica de pinturas

Translated title of the contribution: Blood disorders among workers exposed to a mixture of benzene-toluene-xylene (BTX) in a paint factory

Luis Haro-García, Nadia Vélez-Zamora, Guadalupe Aguilar-Madrid, Susana Guerrero-Rivera, Vanessa Sánchez-Escalante, Sergio R. Muñoz, Edward Mezones-Holguín, Cuauhtémoc Juárez-Pérez

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Objectives. Evaluate the three blood cell series and identify the presence of hypochromia, macrocytosis, leucopenia, lymphopenia, and thrombocytopenia in a group of workers exposed to the mixture of benzene-toluene-xylene (BTX). Materials and methods. A cross-sectional study which included 97 workers from a paint factory in Mexico. The participants underwent conventional blood count and tests for potential cumulative daily dose of BTX fumes, to estimate exposure. Results. From the total of workers, 19.6% showed macrocytosis, 18.6%, lymphopenia, hypochromia 10.3%, 7.2% and 5.2% thrombocytopenia leukopenia. The crude association of macrocytosis with exposure to high doses of BTX mixture was the only with statistical significance (OR: 3.6, 95% CI 1.08 to 13.9, P = 0.02), and the base for a logistic regression model (OR: 6.7, 95% CI 1.33 to 13.55, P = 0.02) adjusted for age, alcohol consumption, and smoking. Conclusions. All blood cytological components analyzed demonstrated mild changes, potentially associated with exposure to the mixture of BTX. Macrocytosis could constitute an early manifestation worthy for surveillance.

Translated title of the contributionBlood disorders among workers exposed to a mixture of benzene-toluene-xylene (BTX) in a paint factory
Original languageSpanish
Pages (from-to)181-187
Number of pages7
JournalRevista Peruana de Medicina Experimental y Salud Publica
Volume29
Issue number2
DOIs
StatePublished - 2012
Externally publishedYes

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